Yuan XH - Search Results

1

Discovery of tofacitinib derivatives as orally active antitumor agents based on the scaffold hybridization strategy.

Shi XJ, Wang S, Li XJ, Yuan XH, Cao LJ, Yu B, Liu HM. Shi XJ, et al. Among authors: yuan xh. Eur J Med Chem. 2020 Oct 1;203:112601. doi: 10.1016/j.ejmech.2020.112601. Epub 2020 Jul 12. Eur J Med Chem. 2020. PMID: 32682202

2

Experience-based discovery (EBD) of aryl hydrazines as new scaffolds for the development of LSD1/KDM1A inhibitors.

Li ZR, Wang S, Yang L, Yuan XH, Suo FZ, Yu B, Liu HM. Li ZR, et al. Among authors: yuan xh. Eur J Med Chem. 2019 Mar 15;166:432-444. doi: 10.1016/j.ejmech.2019.01.075. Epub 2019 Feb 2. Eur J Med Chem. 2019. PMID: 30739825

3

Synthesis, structure-activity relationship studies and biological characterization of new [1,2,4]triazolo[1,5-a]pyrimidine-based LSD1/KDM1A inhibitors.

Wang S, Li ZR, Suo FZ, Yuan XH, Yu B, Liu HM. Wang S, et al. Among authors: yuan xh. Eur J Med Chem. 2019 Apr 1;167:388-401. doi: 10.1016/j.ejmech.2019.02.039. Epub 2019 Feb 13. Eur J Med Chem. 2019. PMID: 30780087

4

Drug repurposing: Discovery of troxipide analogs as potent antitumor agents.

Lu N, Huo JL, Wang S, Yuan XH, Liu HM. Lu N, et al. Among authors: yuan xh. Eur J Med Chem. 2020 Sep 15;202:112471. doi: 10.1016/j.ejmech.2020.112471. Epub 2020 Jun 26. Eur J Med Chem. 2020. PMID: 32619887 Free PMC article.

5

Discovery of new [1,2,4] Triazolo[1,5-a]Pyrimidine derivatives that Kill gastric cancer cells via the mitochondria pathway.

Wang S, Ma XB, Yuan XH, Yu B, Xu YC, Liu HM. Wang S, et al. Among authors: yuan xh. Eur J Med Chem. 2020 Oct 1;203:112630. doi: 10.1016/j.ejmech.2020.112630. Epub 2020 Jul 12. Eur J Med Chem. 2020. PMID: 32683165

6

Structure-Based Design, Synthesis, and Biological Evaluation of New Triazolo[1,5-a]Pyrimidine Derivatives as Highly Potent and Orally Active ABCB1 Modulators.

Wang S, Wang SQ, Teng QX, Yang L, Lei ZN, Yuan XH, Huo JF, Chen XB, Wang M, Yu B, Chen ZS, Liu HM. Wang S, et al. Among authors: yuan xh. J Med Chem. 2020 Dec 24;63(24):15979-15996. doi: 10.1021/acs.jmedchem.0c01741. Epub 2020 Dec 5. J Med Chem. 2020. PMID: 33280384

7

Discovery of [1,2,4]triazolo[1,5-a]pyrimidines derivatives as potential anticancer agents.

Huo JL, Wang S, Yuan XH, Yu B, Zhao W, Liu HM. Huo JL, et al. Among authors: yuan xh. Eur J Med Chem. 2021 Feb 5;211:113108. doi: 10.1016/j.ejmech.2020.113108. Epub 2020 Dec 24. Eur J Med Chem. 2021. PMID: 33385852

8

FDA-approved pyrimidine-fused bicyclic heterocycles for cancer therapy: Synthesis and clinical application.

Wang S, Yuan XH, Wang SQ, Zhao W, Chen XB, Yu B. Wang S, et al. Among authors: yuan xh. Eur J Med Chem. 2021 Mar 15;214:113218. doi: 10.1016/j.ejmech.2021.113218. Epub 2021 Jan 24. Eur J Med Chem. 2021. PMID: 33540357 Review.

9

[Analysis of Carbon Emission Reduction Potential in the Pilot of a "Zero-free City" in Chongqing].

Liu YT, Zhang Q, Yuan XH, Xie WH. Liu YT, et al. Among authors: yuan xh. Huan Jing Ke Xue. 2025 Jan 8;46(1):88-99. doi: 10.13227/j.hjkx.202401063. Huan Jing Ke Xue. 2025. PMID: 39721617 Chinese.

10

Transcriptome Proffling, Physiological and Biochemical Analyses Reveal Comprehensive Insights into Cadmium Stress in Myricaria laxiflora.

Peng Y, Yang YB, Wang JC, Tian MY, Yuan XH, Yang ZJ, Zuo YW, Deng HP. Peng Y, et al. Among authors: yuan xh. Plants (Basel). 2024 Dec 6;13(23):3433. doi: 10.3390/plants13233433. Plants (Basel). 2024. PMID: 39683226 Free PMC article.

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