Hotchkiss RS - Search Results

1

Severe immunosuppression and not a cytokine storm characterizes COVID-19 infections.

Remy KE, Mazer M, Striker DA, Ellebedy AH, Walton AH, Unsinger J, Blood TM, Mudd PA, Yi DJ, Mannion DA, Osborne DF, Martin RS, Anand NJ, Bosanquet JP, Blood J, Drewry AM, Caldwell CC, Turnbull IR, Brakenridge SC, Moldwawer LL, Hotchkiss RS. Remy KE, et al. Among authors: hotchkiss rs. JCI Insight. 2020 Sep 3;5(17):e140329. doi: 10.1172/jci.insight.140329. JCI Insight. 2020. PMID: 32687484 Free PMC article.

2

Depletion of dendritic cells, but not macrophages, in patients with sepsis.

Hotchkiss RS, Tinsley KW, Swanson PE, Grayson MH, Osborne DF, Wagner TH, Cobb JP, Coopersmith C, Karl IE. Hotchkiss RS, et al. J Immunol. 2002 Mar 1;168(5):2493-500. doi: 10.4049/jimmunol.168.5.2493. J Immunol. 2002. PMID: 11859143

3

Effects of age on mortality and antibiotic efficacy in cecal ligation and puncture.

Turnbull IR, Wlzorek JJ, Osborne D, Hotchkiss RS, Coopersmith CM, Buchman TG. Turnbull IR, et al. Among authors: hotchkiss rs. Shock. 2003 Apr;19(4):310-3. doi: 10.1097/00024382-200304000-00003. Shock. 2003. PMID: 12688540

4

Adoptive transfer of apoptotic splenocytes worsens survival, whereas adoptive transfer of necrotic splenocytes improves survival in sepsis.

Hotchkiss RS, Chang KC, Grayson MH, Tinsley KW, Dunne BS, Davis CG, Osborne DF, Karl IE. Hotchkiss RS, et al. Proc Natl Acad Sci U S A. 2003 May 27;100(11):6724-9. doi: 10.1073/pnas.1031788100. Epub 2003 May 7. Proc Natl Acad Sci U S A. 2003. PMID: 12736377 Free PMC article.

5

Antibiotics improve survival and alter the inflammatory profile in a murine model of sepsis from Pseudomonas aeruginosa pneumonia.

Coopersmith CM, Amiot DM 2nd, Stromberg PE, Dunne WM, Davis CG, Osborne DF, Husain KD, Turnbull IR, Karl IE, Hotchkiss RS, Buchman TG. Coopersmith CM, et al. Among authors: hotchkiss rs. Shock. 2003 May;19(5):408-14. doi: 10.1097/01.shk.0000054370.24363.ee. Shock. 2003. PMID: 12744482

6

Sepsis induces apoptosis and profound depletion of splenic interdigitating and follicular dendritic cells.

Tinsley KW, Grayson MH, Swanson PE, Drewry AM, Chang KC, Karl IE, Hotchkiss RS. Tinsley KW, et al. Among authors: hotchkiss rs. J Immunol. 2003 Jul 15;171(2):909-14. doi: 10.4049/jimmunol.171.2.909. J Immunol. 2003. PMID: 12847261

7

Antibiotics improve survival in sepsis independent of injury severity but do not change mortality in mice with markedly elevated interleukin 6 levels.

Turnbull IR, Javadi P, Buchman TG, Hotchkiss RS, Karl IE, Coopersmith CM. Turnbull IR, et al. Among authors: hotchkiss rs. Shock. 2004 Feb;21(2):121-5. doi: 10.1097/01.shk.0000108399.56565.e7. Shock. 2004. PMID: 14752284

8

High-dose exogenous iron following cecal ligation and puncture increases mortality rate in mice and is associated with an increase in gut epithelial and splenic apoptosis.

Javadi P, Buchman TG, Stromberg PE, Husain KD, Dunne WM, Woolsey CA, Turnbull IR, Hotchkiss RS, Karl IE, Coopersmith CM. Javadi P, et al. Among authors: hotchkiss rs. Crit Care Med. 2004 May;32(5):1178-85. doi: 10.1097/01.ccm.0000124878.02614.4c. Crit Care Med. 2004. PMID: 15190970

9

Age disproportionately increases sepsis-induced apoptosis in the spleen and gut epithelium.

Turnbull IR, Buchman TG, Javadi P, Woolsey CA, Hotchkiss RS, Karl IE, Coopersmith CM. Turnbull IR, et al. Among authors: hotchkiss rs. Shock. 2004 Oct;22(4):364-8. doi: 10.1097/01.shk.0000142552.77473.7d. Shock. 2004. PMID: 15377893

10

Iron dysregulation combined with aging prevents sepsis-induced apoptosis.

Javadi P, Buchman TG, Stromberg PE, Turnbull IR, Vyas D, Hotchkiss RS, Karl IE, Coopersmith CM. Javadi P, et al. Among authors: hotchkiss rs. J Surg Res. 2005 Sep;128(1):37-44. doi: 10.1016/j.jss.2005.03.022. J Surg Res. 2005. PMID: 15921699 Free PMC article.

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