Kikelj D - Search Results

1

Discovery of new ATP-competitive inhibitors of human DNA topoisomerase IIα through screening of bacterial topoisomerase inhibitors.

Skok Ž, Durcik M, Gramec Skledar D, Barančoková M, Peterlin Mašič L, Tomašič T, Zega A, Kikelj D, Zidar N, Ilaš J. Skok Ž, et al. Among authors: kikelj d. Bioorg Chem. 2020 Sep;102:104049. doi: 10.1016/j.bioorg.2020.104049. Epub 2020 Jun 29. Bioorg Chem. 2020. PMID: 32688116

2

Design and structure-activity relationship of thrombin inhibitors with an azaphenylalanine scaffold: potency and selectivity enhancements via P2 optimization.

Zega A, Mlinsek G, Sepic P, Golic Grdadolnik S, Solmajer T, Tschopp TB, Steiner B, Kikelj D, Urleb U. Zega A, et al. Among authors: kikelj d. Bioorg Med Chem. 2001 Oct;9(10):2745-56. doi: 10.1016/s0968-0896(01)00202-4. Bioorg Med Chem. 2001. PMID: 11557360

3

Novel thrombin inhibitors incorporating non-basic partially saturated heterobicyclic P1-arginine mimetics.

Peterlin-Masic L, Mlinsek G, Solmajer T, Trampus-Bakija A, Stegnar M, Kikelj D. Peterlin-Masic L, et al. Among authors: kikelj d. Bioorg Med Chem Lett. 2003 Mar 10;13(5):789-94. doi: 10.1016/s0960-894x(03)00030-1. Bioorg Med Chem Lett. 2003. PMID: 12617892

4

Selective 3-amino-2-pyridinone acetamide thrombin inhibitors incorporating weakly basic partially saturated heterobicyclic P1-arginine mimetics.

Peterlin-Masic L, Kranjc A, Marinko P, Mlinsek G, Solmajer T, Stegnar M, Kikelj D. Peterlin-Masic L, et al. Among authors: kikelj d. Bioorg Med Chem Lett. 2003 Oct 6;13(19):3171-6. doi: 10.1016/s0960-894x(03)00717-0. Bioorg Med Chem Lett. 2003. PMID: 12951087

5

Novel thrombin inhibitors incorporating weakly basic heterobicyclic P1-arginine mimetics: optimization via modification of P1 and P3 moieties.

Kranjc A, Peterlin-Masic L, Ilas J, Prezelj A, Stegnar M, Kikelj D. Kranjc A, et al. Among authors: kikelj d. Bioorg Med Chem Lett. 2004 Jun 21;14(12):3251-6. doi: 10.1016/j.bmcl.2004.03.085. Bioorg Med Chem Lett. 2004. PMID: 15149685

6

Phosphonate inhibitors of antigen 85C, a crucial enzyme involved in the biosynthesis of the Mycobacterium tuberculosis cell wall.

Gobec S, Plantan I, Mravljak J, Wilson RA, Besra GS, Kikelj D. Gobec S, et al. Among authors: kikelj d. Bioorg Med Chem Lett. 2004 Jul 5;14(13):3559-62. doi: 10.1016/j.bmcl.2004.04.052. Bioorg Med Chem Lett. 2004. PMID: 15177473

7

Toward a novel class of antithrombotic compounds with dual function. Discovery of 1,4-benzoxazin-3(4H)-one derivatives possessing thrombin inhibitory and fibrinogen receptor antagonistic activities.

Stefanic Anderluh P, Anderluh M, Ilas J, Mravljak J, Sollner Dolenc M, Stegnar M, Kikelj D. Stefanic Anderluh P, et al. Among authors: kikelj d. J Med Chem. 2005 May 5;48(9):3110-3. doi: 10.1021/jm048984g. J Med Chem. 2005. PMID: 15857114

8

Recent advances in the discovery of tissue factor/factor VIIa inhibitors and dual inhibitors of factor VIIa/factor Xa.

Kranjc A, Kikelj D, Peterlin-Masic L. Kranjc A, et al. Among authors: kikelj d. Curr Pharm Des. 2005;11(32):4207-27. doi: 10.2174/138161205774913282. Curr Pharm Des. 2005. PMID: 16375741 Review.

9

Peptides and pseudopeptides incorporating D-Phe-Pro-Arg and Arg-Gly-Asp lead sequences as potential antithrombotic agents.

Ilas J, Hudecz F, Süli-Vargha H, Kikelj D. Ilas J, et al. Among authors: kikelj d. J Pept Sci. 2008 Aug;14(8):946-53. doi: 10.1002/psc.1030. J Pept Sci. 2008. PMID: 18383437

10

Novel potent and selective thrombin inhibitors based on a central 1,4-benzoxazin-3(4H)-one scaffold.

Ilas J, Tomasić T, Kikelj D. Ilas J, et al. Among authors: kikelj d. J Med Chem. 2008 May 8;51(9):2863-7. doi: 10.1021/jm701622y. Epub 2008 Apr 16. J Med Chem. 2008. PMID: 18412326

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

113 results

Search Page

Filters