Walter P - Search Results

1

Inhibition of the integrated stress response by viral proteins that block p-eIF2-eIF2B association.

Rabouw HH, Visser LJ, Passchier TC, Langereis MA, Liu F, Giansanti P, van Vliet ALW, Dekker JG, van der Grein SG, Saucedo JG, Anand AA, Trellet ME, Bonvin AMJJ, Walter P, Heck AJR, de Groot RJ, van Kuppeveld FJM. Rabouw HH, et al. Among authors: walter p. Nat Microbiol. 2020 Nov;5(11):1361-1373. doi: 10.1038/s41564-020-0759-0. Epub 2020 Jul 20. Nat Microbiol. 2020. PMID: 32690955

2

Messenger RNA targeting to endoplasmic reticulum stress signalling sites.

Aragón T, van Anken E, Pincus D, Serafimova IM, Korennykh AV, Rubio CA, Walter P. Aragón T, et al. Among authors: walter p. Nature. 2009 Feb 5;457(7230):736-40. doi: 10.1038/nature07641. Epub 2008 Dec 14. Nature. 2009. PMID: 19079237 Free PMC article.

3

Pharmacological brake-release of mRNA translation enhances cognitive memory.

Sidrauski C, Acosta-Alvear D, Khoutorsky A, Vedantham P, Hearn BR, Li H, Gamache K, Gallagher CM, Ang KK, Wilson C, Okreglak V, Ashkenazi A, Hann B, Nader K, Arkin MR, Renslo AR, Sonenberg N, Walter P. Sidrauski C, et al. Among authors: walter p. Elife. 2013 May 28;2:e00498. doi: 10.7554/eLife.00498. Elife. 2013. PMID: 23741617 Free PMC article.

4

Translational control of mGluR-dependent long-term depression and object-place learning by eIF2α.

Di Prisco GV, Huang W, Buffington SA, Hsu CC, Bonnen PE, Placzek AN, Sidrauski C, Krnjević K, Kaufman RJ, Walter P, Costa-Mattioli M. Di Prisco GV, et al. Among authors: walter p. Nat Neurosci. 2014 Aug;17(8):1073-82. doi: 10.1038/nn.3754. Epub 2014 Jun 29. Nat Neurosci. 2014. PMID: 24974795 Free PMC article.

5

The small molecule ISRIB reverses the effects of eIF2α phosphorylation on translation and stress granule assembly.

Sidrauski C, McGeachy AM, Ingolia NT, Walter P. Sidrauski C, et al. Among authors: walter p. Elife. 2015 Feb 26;4:e05033. doi: 10.7554/eLife.05033. Elife. 2015. PMID: 25719440 Free PMC article.

6

Pharmacological dimerization and activation of the exchange factor eIF2B antagonizes the integrated stress response.

Sidrauski C, Tsai JC, Kampmann M, Hearn BR, Vedantham P, Jaishankar P, Sokabe M, Mendez AS, Newton BW, Tang EL, Verschueren E, Johnson JR, Krogan NJ, Fraser CS, Weissman JS, Renslo AR, Walter P. Sidrauski C, et al. Among authors: walter p. Elife. 2015 Apr 15;4:e07314. doi: 10.7554/eLife.07314. Elife. 2015. PMID: 25875391 Free PMC article.

7

Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response.

Hearn BR, Jaishankar P, Sidrauski C, Tsai JC, Vedantham P, Fontaine SD, Walter P, Renslo AR. Hearn BR, et al. Among authors: walter p. ChemMedChem. 2016 Apr 19;11(8):870-80. doi: 10.1002/cmdc.201500483. Epub 2016 Jan 20. ChemMedChem. 2016. PMID: 26789650

8

Translation from the 5' untranslated region shapes the integrated stress response.

Starck SR, Tsai JC, Chen K, Shodiya M, Wang L, Yahiro K, Martins-Green M, Shastri N, Walter P. Starck SR, et al. Among authors: walter p. Science. 2016 Jan 29;351(6272):aad3867. doi: 10.1126/science.aad3867. Science. 2016. PMID: 26823435 Free PMC article.

9

Inhibition of the integrated stress response reverses cognitive deficits after traumatic brain injury.

Chou A, Krukowski K, Jopson T, Zhu PJ, Costa-Mattioli M, Walter P, Rosi S. Chou A, et al. Among authors: walter p. Proc Natl Acad Sci U S A. 2017 Aug 1;114(31):E6420-E6426. doi: 10.1073/pnas.1707661114. Epub 2017 Jul 10. Proc Natl Acad Sci U S A. 2017. PMID: 28696288 Free PMC article.

10

Structure of the nucleotide exchange factor eIF2B reveals mechanism of memory-enhancing molecule.

Tsai JC, Miller-Vedam LE, Anand AA, Jaishankar P, Nguyen HC, Renslo AR, Frost A, Walter P. Tsai JC, et al. Among authors: walter p. Science. 2018 Mar 30;359(6383):eaaq0939. doi: 10.1126/science.aaq0939. Science. 2018. PMID: 29599213 Free PMC article.

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