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Page 1
Signalling input from divergent pathways subverts B cell transformation.
Chan LN, Murakami MA, Robinson ME, Caeser R, Sadras T, Lee J, Cosgun KN, Kume K, Khairnar V, Xiao G, Ahmed MA, Aghania E, Deb G, Hurtz C, Shojaee S, Hong C, Pölönen P, Nix MA, Chen Z, Chen CW, Chen J, Vogt A, Heinäniemi M, Lohi O, Wiita AP, Izraeli S, Geng H, Weinstock DM, Müschen M. Chan LN, et al. Among authors: polonen p. Nature. 2020 Jul;583(7818):845-851. doi: 10.1038/s41586-020-2513-4. Epub 2020 Jul 22. Nature. 2020. PMID: 32699415 Free PMC article.
Role of the Keap1-Nrf2 pathway in cancer.
Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL. Leinonen HM, et al. Among authors: polonen p. Adv Cancer Res. 2014;122:281-320. doi: 10.1016/B978-0-12-420117-0.00008-6. Adv Cancer Res. 2014. PMID: 24974185 Review.
Dysregulation of the Keap1-Nrf2 pathway in cancer.
Leinonen HM, Kansanen E, Pölönen P, Heinäniemi M, Levonen AL. Leinonen HM, et al. Among authors: polonen p. Biochem Soc Trans. 2015 Aug;43(4):645-9. doi: 10.1042/BST20150048. Epub 2015 Aug 3. Biochem Soc Trans. 2015. PMID: 26551706 Review.
In silico and preclinical drug screening identifies dasatinib as a targeted therapy for T-ALL.
Laukkanen S, Grönroos T, Pölönen P, Kuusanmäki H, Mehtonen J, Cloos J, Ossenkoppele G, Gjertsen B, Øystein B, Heckman C, Heinäniemi M, Kontro M, Lohi O. Laukkanen S, et al. Among authors: polonen p. Blood Cancer J. 2017 Sep 8;7(9):e604. doi: 10.1038/bcj.2017.87. Blood Cancer J. 2017. PMID: 28885610 Free PMC article. No abstract available.
Hemap: An Interactive Online Resource for Characterizing Molecular Phenotypes across Hematologic Malignancies.
Pölönen P, Mehtonen J, Lin J, Liuksiala T, Häyrynen S, Teppo S, Mäkinen A, Kumar A, Malani D, Pohjolainen V, Porkka K, Heckman CA, May P, Hautamäki V, Granberg KJ, Lohi O, Nykter M, Heinäniemi M. Pölönen P, et al. Cancer Res. 2019 May 15;79(10):2466-2479. doi: 10.1158/0008-5472.CAN-18-2970. Epub 2019 Apr 2. Cancer Res. 2019. PMID: 30940663
Immunogenomic Landscape of Hematological Malignancies.
Dufva O, Pölönen P, Brück O, Keränen MAI, Klievink J, Mehtonen J, Huuhtanen J, Kumar A, Malani D, Siitonen S, Kankainen M, Ghimire B, Lahtela J, Mattila P, Vähä-Koskela M, Wennerberg K, Granberg K, Leivonen SK, Meriranta L, Heckman C, Leppä S, Nykter M, Lohi O, Heinäniemi M, Mustjoki S. Dufva O, et al. Among authors: polonen p. Cancer Cell. 2020 Sep 14;38(3):380-399.e13. doi: 10.1016/j.ccell.2020.06.002. Epub 2020 Jul 9. Cancer Cell. 2020. PMID: 32649887 Free article.
Profiling of Primary and Mature miRNA Expression in Atherosclerosis-Associated Cell Types.
Moreau PR, Tomas Bosch V, Bouvy-Liivrand M, Õunap K, Örd T, Pulkkinen HH, Pölönen P, Heinäniemi M, Ylä-Herttuala S, Laakkonen JP, Linna-Kuosmanen S, Kaikkonen MU. Moreau PR, et al. Among authors: polonen p. Arterioscler Thromb Vasc Biol. 2021 Jul;41(7):2149-2167. doi: 10.1161/ATVBAHA.121.315579. Epub 2021 May 13. Arterioscler Thromb Vasc Biol. 2021. PMID: 33980036 Free PMC article.
Sequential drug treatment targeting cell cycle and cell fate regulatory programs blocks non-genetic cancer evolution in acute lymphoblastic leukemia.
Malyukova A, Lahnalampi M, Falqués-Costa T, Pölönen P, Sipola M, Mehtonen J, Teppo S, Akopyan K, Viiliainen J, Lohi O, Hagström-Andersson AK, Heinäniemi M, Sangfelt O. Malyukova A, et al. Among authors: polonen p. Genome Biol. 2024 May 31;25(1):143. doi: 10.1186/s13059-024-03260-4. Genome Biol. 2024. PMID: 38822412 Free PMC article.
45 results