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Page 1
The Meningioma Enhancer Landscape Delineates Novel Subgroups and Drives Druggable Dependencies.
Prager BC, Vasudevan HN, Dixit D, Bernatchez JA, Wu Q, Wallace LC, Bhargava S, Lee D, King BH, Morton AR, Gimple RC, Pekmezci M, Zhu Z, Siqueira-Neto JL, Wang X, Xie Q, Chen C, Barnett GH, Vogelbaum MA, Mack SC, Chavez L, Perry A, Raleigh DR, Rich JN. Prager BC, et al. Among authors: mack sc. Cancer Discov. 2020 Nov;10(11):1722-1741. doi: 10.1158/2159-8290.CD-20-0160. Epub 2020 Jul 23. Cancer Discov. 2020. PMID: 32703768 Free PMC article.
CDC20 maintains tumor initiating cells.
Xie Q, Wu Q, Mack SC, Yang K, Kim L, Hubert CG, Flavahan WA, Chu C, Bao S, Rich JN. Xie Q, et al. Among authors: mack sc. Oncotarget. 2015 May 30;6(15):13241-54. doi: 10.18632/oncotarget.3676. Oncotarget. 2015. PMID: 25938542 Free PMC article.
Cancer stem cells in glioblastoma.
Lathia JD, Mack SC, Mulkearns-Hubert EE, Valentim CL, Rich JN. Lathia JD, et al. Among authors: mack sc. Genes Dev. 2015 Jun 15;29(12):1203-17. doi: 10.1101/gad.261982.115. Genes Dev. 2015. PMID: 26109046 Free PMC article. Review.
Preferential Iron Trafficking Characterizes Glioblastoma Stem-like Cells.
Schonberg DL, Miller TE, Wu Q, Flavahan WA, Das NK, Hale JS, Hubert CG, Mack SC, Jarrar AM, Karl RT, Rosager AM, Nixon AM, Tesar PJ, Hamerlik P, Kristensen BW, Horbinski C, Connor JR, Fox PL, Lathia JD, Rich JN. Schonberg DL, et al. Among authors: mack sc. Cancer Cell. 2015 Oct 12;28(4):441-455. doi: 10.1016/j.ccell.2015.09.002. Cancer Cell. 2015. PMID: 26461092 Free PMC article.
MLL5 Orchestrates a Cancer Self-Renewal State by Repressing the Histone Variant H3.3 and Globally Reorganizing Chromatin.
Gallo M, Coutinho FJ, Vanner RJ, Gayden T, Mack SC, Murison A, Remke M, Li R, Takayama N, Desai K, Lee L, Lan X, Park NI, Barsyte-Lovejoy D, Smil D, Sturm D, Kushida MM, Head R, Cusimano MD, Bernstein M, Clarke ID, Dick JE, Pfister SM, Rich JN, Arrowsmith CH, Taylor MD, Jabado N, Bazett-Jones DP, Lupien M, Dirks PB. Gallo M, et al. Among authors: mack sc. Cancer Cell. 2015 Dec 14;28(6):715-729. doi: 10.1016/j.ccell.2015.10.005. Epub 2015 Nov 25. Cancer Cell. 2015. PMID: 26626085 Free article.
An epigenetic gateway to brain tumor cell identity.
Mack SC, Hubert CG, Miller TE, Taylor MD, Rich JN. Mack SC, et al. Nat Neurosci. 2016 Jan;19(1):10-9. doi: 10.1038/nn.4190. Nat Neurosci. 2016. PMID: 26713744 Free PMC article. Review.
A Three-Dimensional Organoid Culture System Derived from Human Glioblastomas Recapitulates the Hypoxic Gradients and Cancer Stem Cell Heterogeneity of Tumors Found In Vivo.
Hubert CG, Rivera M, Spangler LC, Wu Q, Mack SC, Prager BC, Couce M, McLendon RE, Sloan AE, Rich JN. Hubert CG, et al. Among authors: mack sc. Cancer Res. 2016 Apr 15;76(8):2465-77. doi: 10.1158/0008-5472.CAN-15-2402. Epub 2016 Feb 19. Cancer Res. 2016. PMID: 26896279 Free PMC article.
117 results