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A Randomized, Blinded, Vehicle-Controlled Dose-Ranging Study to Evaluate and Characterize Remdesivir Efficacy Against Ebola Virus in Rhesus Macaques.
Zumbrun EE, Garvey CB, Wells JB, Lynn GC, Van Tongeren SA, Steffens JT, Wetzel KS, Wetzel DL, Esham HL, Garza NL, Lee ED, Scruggs JL, Rossi FD, Brown ES, Weidner JM, Gomba LM, O'Brien KA, Jay AN, Zeng X, Akers KS, Kallgren PA, Englund E, Meinig JM, Kugelman JR, Moore JL, Bloomfield HA, Norris SL, Bryan T, Scheuerell CH, Walters J, Mollova N, Blair C, Babusis D, Cihlar T, Porter DP, Singh B, Hedskog C, Bavari S, Warren TK, Bannister R. Zumbrun EE, et al. Among authors: bavari s. Viruses. 2024 Dec 18;16(12):1934. doi: 10.3390/v16121934. Viruses. 2024. PMID: 39772240 Free PMC article.
Recombinant chimeric horsepox virus (TNX-801) is attenuated relative to vaccinia virus strains in both in vitro and in vivo models.
Trefry SV, Awasthi M, Raney CN, Cregger AL, Gonzales CA, Layton BL, Enamorado RN, Martinez NA, Gohegan DS, Masoud-Bahnamiri M, Cho JY, Myscofski DM, Moulaei T, Ziółkowska NE, Goebel SJ, Lederman S, Bavari S, Nasar F. Trefry SV, et al. Among authors: bavari s. mSphere. 2024 Dec 19;9(12):e0026524. doi: 10.1128/msphere.00265-24. Epub 2024 Nov 13. mSphere. 2024. PMID: 39535212 Free PMC article.
HSP90 is part of a protein complex with the L polymerase of Rift Valley fever phlebovirus and prevents its degradation by the proteasome during the viral genome replication/transcription stage.
Alem F, Brahms A, Tarasaki K, Omole S, Kehn-Hall K, Schmaljohn CS, Bavari S, Makino S, Hakami RM. Alem F, et al. Among authors: bavari s. Front Cell Infect Microbiol. 2024 May 10;14:1331755. doi: 10.3389/fcimb.2024.1331755. eCollection 2024. Front Cell Infect Microbiol. 2024. PMID: 38800833 Free PMC article.
Immunogenicity and Efficacy of TNX-1800, A Live Virus Recombinant Poxvirus Vaccine Candidate, against SARS-CoV-2 Challenge in Nonhuman Primates.
Awasthi M, Macaluso A, Myscofski D, Prigge J, Koide F, Noyce RS, Fogarty S, Stillwell H, Goebel SJ, Daugherty B, Nasar F, Bavari S, Lederman S. Awasthi M, et al. Among authors: bavari s. Vaccines (Basel). 2023 Nov 2;11(11):1682. doi: 10.3390/vaccines11111682. Vaccines (Basel). 2023. PMID: 38006014 Free PMC article.
Development of a rapid image-based high-content imaging screening assay to evaluate therapeutic antibodies against the monkeypox virus.
Kota KP, Ziółkowska NE, Wei J, Peng J, Ordonez D, Raney C, Prigge J, Hooper JW, Awasthi M, Goebel SJ, Zabel BA, Nasar F, Lederman S, Bavari S. Kota KP, et al. Among authors: bavari s. Antiviral Res. 2023 Feb;210:105513. doi: 10.1016/j.antiviral.2022.105513. Epub 2022 Dec 30. Antiviral Res. 2023. PMID: 36592670 Free PMC article.
326 results