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The novel SOD mimetic GC4419 increases cancer cell killing with sensitization to ionizing radiation while protecting normal cells.
Free Radic Biol Med. 2020 Nov 20;160:630-642. doi: 10.1016/j.freeradbiomed.2020.07.032. Epub 2020 Jul 30.
Free Radic Biol Med. 2020.
PMID: 32739595
Free PMC article.
Chronic cigarette smoke exposure triggers a vicious cycle of leukocyte and endothelial-mediated oxidant stress that results in vascular dysfunction.
El-Mahdy MA, Abdelghany TM, Hemann C, Ewees MG, Mahgoup EM, Eid MS, Shalaan MT, Alzarie YA, Zweier JL.
El-Mahdy MA, et al. Among authors: alzarie ya.
Am J Physiol Heart Circ Physiol. 2020 Jul 1;319(1):H51-H65. doi: 10.1152/ajpheart.00657.2019. Epub 2020 May 15.
Am J Physiol Heart Circ Physiol. 2020.
PMID: 32412791
Free PMC article.
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Inhibition of CD38 with the Thiazoloquin(az)olin(on)e 78c Protects the Heart against Postischemic Injury.
Boslett J, Reddy N, Alzarie YA, Zweier JL.
Boslett J, et al. Among authors: alzarie ya.
J Pharmacol Exp Ther. 2019 Apr;369(1):55-64. doi: 10.1124/jpet.118.254557. Epub 2019 Jan 11.
J Pharmacol Exp Ther. 2019.
PMID: 30635470
Free PMC article.
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Trityl radicals in perfluorocarbon emulsions as stable, sensitive, and biocompatible oximetry probes.
Dhimitruka I, Alzarie YA, Hemann C, Samouilov A, Zweier JL.
Dhimitruka I, et al. Among authors: alzarie ya.
Bioorg Med Chem Lett. 2016 Dec 1;26(23):5685-5688. doi: 10.1016/j.bmcl.2016.10.066. Epub 2016 Oct 24.
Bioorg Med Chem Lett. 2016.
PMID: 27836400
Free PMC article.
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