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Page 1
Cerebral Microvascular Injury in Severe COVID-19.
Conklin J, Frosch MP, Mukerji S, Rapalino O, Maher M, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux J, Sabeti P, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL. Conklin J, et al. Among authors: lemieux j. medRxiv [Preprint]. 2020 Jul 24:2020.07.21.20159376. doi: 10.1101/2020.07.21.20159376. medRxiv. 2020. Update in: J Neurol Sci. 2021 Feb 15;421:117308. doi: 10.1016/j.jns.2021.117308 PMID: 32743599 Free PMC article. Updated. Preprint.
Integrated sample inactivation, amplification, and Cas13-based detection of SARS-CoV-2.
Arizti-Sanz J, Freije CA, Stanton AC, Boehm CK, Petros BA, Siddiqui S, Shaw BM, Adams G, Kosoko-Thoroddsen TF, Kemball ME, Gross R, Wronka L, Caviness K, Hensley LE, Bergman NH, MacInnis BL, Lemieux JE, Sabeti PC, Myhrvold C. Arizti-Sanz J, et al. Among authors: lemieux je. bioRxiv [Preprint]. 2020 May 28:2020.05.28.119131. doi: 10.1101/2020.05.28.119131. bioRxiv. 2020. Update in: Nat Commun. 2020 Nov 20;11(1):5921. doi: 10.1038/s41467-020-19097-x PMID: 32511415 Free PMC article. Updated. Preprint.
Phylogenetic analysis of SARS-CoV-2 in the Boston area highlights the role of recurrent importation and superspreading events.
Lemieux JE, Siddle KJ, Shaw BM, Loreth C, Schaffner SF, Gladden-Young A, Adams G, Fink T, Tomkins-Tinch CH, Krasilnikova LA, DeRuff KC, Rudy M, Bauer MR, Lagerborg KA, Normandin E, Chapman SB, Reilly SK, Anahtar MN, Lin AE, Carter A, Myhrvold C, Kemball ME, Chaluvadi S, Cusick C, Flowers K, Neumann A, Cerrato F, Farhat M, Slater D, Harris JB, Branda J, Hooper D, Gaeta JM, Baggett TP, O'Connell J, Gnirke A, Lieberman TD, Philippakis A, Burns M, Brown CM, Luban J, Ryan ET, Turbett SE, LaRocque RC, Hanage WP, Gallagher GR, Madoff LC, Smole S, Pierce VM, Rosenberg E, Sabeti PC, Park DJ, Maclnnis BL. Lemieux JE, et al. medRxiv [Preprint]. 2020 Aug 25:2020.08.23.20178236. doi: 10.1101/2020.08.23.20178236. medRxiv. 2020. Update in: Science. 2021 Feb 5;371(6529):eabe3261. doi: 10.1126/science.abe3261 PMID: 32869040 Free PMC article. Updated. Preprint.
Development of a qualitative real-time RT-PCR assay for the detection of SARS-CoV-2: A guide and case study in setting up an emergency-use, laboratory-developed molecular assay.
Anahtar MN, Shaw B, Slater D, Byrne E, Botti-Lodovico Y, Adams G, Schaffner S, Eversley J, McGrath G, Gogakos T, Lennerz J, Desai Marble H, Ritterhouse LL, Batten J, Georgantas NZ, Pellerin R, Signorelli S, Thierauf J, Kemball M, Happi C, Grant DS, Ndiaye D, Siddle KJ, Mehta SB, Harris J, Ryan ET, Pierce V, LaRocque R, Lemieux JE, Sabeti P, Rosenberg E, Branda J, Turbett SE. Anahtar MN, et al. Among authors: lemieux je. medRxiv [Preprint]. 2020 Sep 1:2020.08.26.20157297. doi: 10.1101/2020.08.26.20157297. medRxiv. 2020. Update in: J Clin Pathol. 2021 Aug;74(8):496-503. doi: 10.1136/jclinpath-2020-207128 PMID: 32909014 Free PMC article. Updated. Preprint.
Powassan Virus Neuropathology and Genomic Diversity in Patients With Fatal Encephalitis.
Normandin E, Solomon IH, Zamirpour S, Lemieux J, Freije CA, Mukerji SS, Tomkins-Tinch C, Park D, Sabeti PC, Piantadosi A. Normandin E, et al. Among authors: lemieux j. Open Forum Infect Dis. 2020 Aug 29;7(10):ofaa392. doi: 10.1093/ofid/ofaa392. eCollection 2020 Oct. Open Forum Infect Dis. 2020. PMID: 33094116 Free PMC article.
Susceptibility-weighted imaging reveals cerebral microvascular injury in severe COVID-19.
Conklin J, Frosch MP, Mukerji SS, Rapalino O, Maher MD, Schaefer PW, Lev MH, Gonzalez RG, Das S, Champion SN, Magdamo C, Sen P, Harrold GK, Alabsi H, Normandin E, Shaw B, Lemieux JE, Sabeti PC, Branda JA, Brown EN, Westover MB, Huang SY, Edlow BL. Conklin J, et al. Among authors: lemieux je. J Neurol Sci. 2021 Feb 15;421:117308. doi: 10.1016/j.jns.2021.117308. Epub 2021 Jan 15. J Neurol Sci. 2021. PMID: 33497950 Free PMC article.
DNA spike-ins enable confident interpretation of SARS-CoV-2 genomic data from amplicon-based sequencing.
Lagerborg KA, Normandin E, Bauer MR, Adams G, Figueroa K, Loreth C, Gladden-Young A, Shaw B, Pearlman L, Shenoy ES, Hooper D, Pierce VM, Zachary KC, Park DJ, MacInnis BL, Lemieux JE, Sabeti PC, Reilly SK, Siddle KJ. Lagerborg KA, et al. Among authors: lemieux je. bioRxiv [Preprint]. 2021 Mar 16:2021.03.16.435654. doi: 10.1101/2021.03.16.435654. bioRxiv. 2021. PMID: 33758855 Free PMC article. Preprint.
Intrathecal inflammatory responses in the absence of SARS-CoV-2 nucleic acid in the CSF of COVID-19 hospitalized patients.
Normandin E, Holroyd KB, Collens SI, Shaw BM, Siddle KJ, Adams G, Rudy M, Solomon IH, Anahtar MN, Lemieux JE, Trombetta BA, Kivisakk P, Arnold SE, Rapalino O, Piantadosi AL, Sen P, Rosenberg ES, Branda J, Sabeti PC, Mukerji SS. Normandin E, et al. Among authors: lemieux je. J Neurol Sci. 2021 Nov 15;430:120023. doi: 10.1016/j.jns.2021.120023. Epub 2021 Oct 4. J Neurol Sci. 2021. PMID: 34678659 Free PMC article.
Analysis of 6.4 million SARS-CoV-2 genomes identifies mutations associated with fitness.
Obermeyer F, Jankowiak M, Barkas N, Schaffner SF, Pyle JD, Yurkovetskiy L, Bosso M, Park DJ, Babadi M, MacInnis BL, Luban J, Sabeti PC, Lemieux JE. Obermeyer F, et al. Among authors: lemieux je. medRxiv [Preprint]. 2022 Feb 16:2021.09.07.21263228. doi: 10.1101/2021.09.07.21263228. medRxiv. 2022. Update in: Science. 2022 Jun 17;376(6599):1327-1332. doi: 10.1126/science.abm1208 PMID: 35194619 Free PMC article. Updated. Preprint.
The 2022 RSV surge was driven by multiple viral lineages.
Adams G, Moreno GK, Petros BA, Uddin R, Levine Z, Kotzen B, Messer K, Dobbins ST, DeRuff KC, Loreth C, Brock-Fisher T, Schaffner SF, Chaluvadi S, Kanjilal S, Luban J, Ozonoff A, Park D, Turbett S, Siddle KJ, MacInnis BL, Sabeti P, Lemieux J. Adams G, et al. Among authors: lemieux j. medRxiv [Preprint]. 2023 Jan 5:2023.01.04.23284195. doi: 10.1101/2023.01.04.23284195. medRxiv. 2023. Update in: N Engl J Med. 2023 Apr 6;388(14):1335-1337. doi: 10.1056/NEJMc2216153 PMID: 36656774 Free PMC article. Updated. Preprint.
277 results