Van Aerschot A - Search Results

1

Synthesis and structural insights into the binding mode of the albomycin δ1 core and its analogues in complex with their target aminoacyl-tRNA synthetase.

Gadakh B, Vondenhoff G, Pang L, Nautiyal M, De Graef S, Strelkov SV, Weeks SD, Van Aerschot A. Gadakh B, et al. Among authors: van aerschot a. Bioorg Med Chem. 2020 Sep 1;28(17):115645. doi: 10.1016/j.bmc.2020.115645. Epub 2020 Jul 13. Bioorg Med Chem. 2020. PMID: 32773091

2

Synthesis and antiviral activity of 3'-heterocyclic substituted 3'-deoxythymidines.

Wigerinck P, Van Aerschot A, Janssen G, Claes P, Balzarini J, De Clercq E, Herdewijn P. Wigerinck P, et al. Among authors: van aerschot a. J Med Chem. 1990 Feb;33(2):868-73. doi: 10.1021/jm00164a063. J Med Chem. 1990. PMID: 2299650

3

Synthesis and anti-HIV evaluation of 2',3'-dideoxyribo-5-chloropyrimidine analogues: reduced toxicity of 5-chlorinated 2',3'-dideoxynucleosides.

Van Aerschot A, Everaert D, Balzarini J, Augustyns K, Jie L, Janssen G, Peeters O, Blaton N, De Ranter C, De Clercq E, et al. Van Aerschot A, et al. J Med Chem. 1990 Jun;33(6):1833-9. doi: 10.1021/jm00168a046. J Med Chem. 1990. PMID: 2342078

4

3'-Fluoro-2',3'-dideoxy-5-chlorouridine: most selective anti-HIV-1 agent among a series of new 2'- and 3'-fluorinated 2',3'-dideoxynucleoside analogues.

Van Aerschot A, Herdewijn P, Balzarini J, Pauwels R, De Clercq E. Van Aerschot A, et al. J Med Chem. 1989 Aug;32(8):1743-9. doi: 10.1021/jm00128a013. J Med Chem. 1989. PMID: 2754700

5

Identification of a peptide inhibitor against glycosomal phosphoglycerate kinase of Trypanosoma brucei by a synthetic peptide library approach.

Samson I, Kerremans L, Rozenski J, Samyn B, Van Beeumen J, Van Aerschot A, Herdewijn P. Samson I, et al. Among authors: van aerschot a, van beeumen j. Bioorg Med Chem. 1995 Mar;3(3):257-65. doi: 10.1016/0968-0896(95)00020-h. Bioorg Med Chem. 1995. PMID: 7606387

6

Synthesis, biological evaluation, and structure analysis of a series of new 1,5-anhydrohexitol nucleosides.

Verheggen I, Van Aerschot A, Van Meervelt L, Rozenski J, Wiebe L, Snoeck R, Andrei G, Balzarini J, Claes P, De Clercq E, et al. Verheggen I, et al. Among authors: van aerschot a, van meervelt l. J Med Chem. 1995 Mar 3;38(5):826-35. doi: 10.1021/jm00005a010. J Med Chem. 1995. PMID: 7877148

7

Synthesis and antiherpes virus activity of 1,5-anhydrohexitol nucleosides.

Verheggen I, Van Aerschot A, Toppet S, Snoeck R, Janssen G, Balzarini J, De Clercq E, Herdewijn P. Verheggen I, et al. Among authors: van aerschot a. J Med Chem. 1993 Jul 9;36(14):2033-40. doi: 10.1021/jm00066a013. J Med Chem. 1993. PMID: 8393114

8

N6-cyclopentyl-3'-substituted-xylofuranosyladenosines: a new class of non-xanthine adenosine A1 receptor antagonists.

Van Calenbergh S, von Frijtag Drabbe Künzel JK, Blaton NM, Peeters OM, Rozenski J, Van Aerschot A, De Bruyn A, De Keukeleire D, IJzerman AP, Herdewijn P. Van Calenbergh S, et al. Among authors: van aerschot a. J Med Chem. 1997 Nov 7;40(23):3765-72. doi: 10.1021/jm970176k. J Med Chem. 1997. PMID: 9371242

9

New dsDNA binding unnatural oligopeptides with pyrimidine selectivity.

Zhang Z, Chaltin P, Van Aerschot A, Lacey J, Rozenski J, Busson R, Herdewijn P. Zhang Z, et al. Among authors: van aerschot a. Bioorg Med Chem. 2002 Nov;10(11):3401-13. doi: 10.1016/s0968-0896(02)00268-7. Bioorg Med Chem. 2002. PMID: 12213453

10

Aminoacyl-tRNA synthetase inhibitors as potent and synergistic immunosuppressants.

Van de Vijver P, Ostrowski T, Sproat B, Goebels J, Rutgeerts O, Van Aerschot A, Waer M, Herdewijn P. Van de Vijver P, et al. Among authors: van aerschot a. J Med Chem. 2008 May 22;51(10):3020-9. doi: 10.1021/jm8000746. Epub 2008 Apr 26. J Med Chem. 2008. PMID: 18438987

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