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Site-directed M2 proton channel inhibitors enable synergistic combination therapy for rimantadine-resistant pandemic influenza.
Scott C, Kankanala J, Foster TL, Goldhill DH, Bao P, Simmons K, Pingen M, Bentham M, Atkins E, Loundras E, Elderfield R, Claridge JK, Thompson J, Stilwell PR, Tathineni R, McKimmie CS, Targett-Adams P, Schnell JR, Cook GP, Evans S, Barclay WS, Foster R, Griffin S. Scott C, et al. Among authors: simmons k. PLoS Pathog. 2020 Aug 11;16(8):e1008716. doi: 10.1371/journal.ppat.1008716. eCollection 2020 Aug. PLoS Pathog. 2020. PMID: 32780760 Free PMC article.
Structure-based discovery of antibacterial drugs.
Simmons KJ, Chopra I, Fishwick CW. Simmons KJ, et al. Nat Rev Microbiol. 2010 Jul;8(7):501-10. doi: 10.1038/nrmicro2349. Nat Rev Microbiol. 2010. PMID: 20551974 Review.
502 results