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Engineering the Human Fc Region Enables Direct Cell Killing by Cancer Glycan-Targeting Antibodies without the Need for Immune Effector Cells or Complement.
Vankemmelbeke M, McIntosh RS, Chua JX, Kirk T, Daniels I, Patsalidou M, Moss R, Parsons T, Scott D, Harris G, Ramage JM, Spendlove I, Durrant LG. Vankemmelbeke M, et al. Cancer Res. 2020 Aug 15;80(16):3399-3412. doi: 10.1158/0008-5472.CAN-19-3599. Epub 2020 Jun 12. Cancer Res. 2020. PMID: 32532823 Free PMC article.
Cancer cell associated glycans as targets for immunotherapy.
Vankemmelbeke M, Chua JX, Durrant LG. Vankemmelbeke M, et al. Oncoimmunology. 2015 Jul 15;5(1):e1061177. doi: 10.1080/2162402X.2015.1061177. eCollection 2016. Oncoimmunology. 2015. PMID: 26942075 Free PMC article.
Glycan-Based Near-infrared Fluorescent (NIRF) Imaging of Gastrointestinal Tumors: a Preclinical Proof-of-Concept In Vivo Study.
Houvast RD, Baart VM, Bhairosingh SS, Cordfunke RA, Chua JX, Vankemmelbeke M, Parsons T, Kuppen PJK, Durrant LG, Vahrmeijer AL, Sier CFM. Houvast RD, et al. Among authors: vankemmelbeke m. Mol Imaging Biol. 2020 Dec;22(6):1511-1522. doi: 10.1007/s11307-020-01522-8. Epub 2020 Aug 11. Mol Imaging Biol. 2020. PMID: 32780212 Free PMC article.
Targeting Glycans and Heavily Glycosylated Proteins for Tumor Imaging.
Houvast RD, Vankemmelbeke M, Durrant LG, Wuhrer M, Baart VM, Kuppen PJK, de Geus-Oei LF, Vahrmeijer AL, Sier CFM. Houvast RD, et al. Among authors: vankemmelbeke m. Cancers (Basel). 2020 Dec 21;12(12):3870. doi: 10.3390/cancers12123870. Cancers (Basel). 2020. PMID: 33371487 Free PMC article. Review.
40 results