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IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.
Rosa BA, Ahmed M, Singh DK, Choreño-Parra JA, Cole J, Jiménez-Álvarez LA, Rodríguez-Reyna TS, Singh B, Gonzalez O, Carrion R Jr, Schlesinger LS, Martin J, Zúñiga J, Mitreva M, Khader SA, Kaushal D. Rosa BA, et al. Among authors: schlesinger ls. bioRxiv [Preprint]. 2020 Aug 6:2020.08.06.239798. doi: 10.1101/2020.08.06.239798. bioRxiv. 2020. Update in: Commun Biol. 2021 Mar 5;4(1):290. doi: 10.1038/s42003-021-01829-4 PMID: 32793903 Free PMC article. Updated. Preprint.
Targeting innate immunity for tuberculosis vaccination.
Khader SA, Divangahi M, Hanekom W, Hill PC, Maeurer M, Makar KW, Mayer-Barber KD, Mhlanga MM, Nemes E, Schlesinger LS, van Crevel R, Vankayalapati R(, Xavier RJ, Netea MG; Bill and Melinda Gates Foundation Collaboration for TB Vaccine Discovery Innate Immunity Working Group18. Khader SA, et al. Among authors: schlesinger ls. J Clin Invest. 2019 Sep 3;129(9):3482-3491. doi: 10.1172/JCI128877. J Clin Invest. 2019. PMID: 31478909 Free PMC article. Review.
Lethality of SARS-CoV-2 infection in K18 human angiotensin-converting enzyme 2 transgenic mice.
Oladunni FS, Park JG, Pino PA, Gonzalez O, Akhter A, Allué-Guardia A, Olmo-Fontánez A, Gautam S, Garcia-Vilanova A, Ye C, Chiem K, Headley C, Dwivedi V, Parodi LM, Alfson KJ, Staples HM, Schami A, Garcia JI, Whigham A, Platt RN 2nd, Gazi M, Martinez J, Chuba C, Earley S, Rodriguez OH, Mdaki SD, Kavelish KN, Escalona R, Hallam CRA, Christie C, Patterson JL, Anderson TJC, Carrion R Jr, Dick EJ Jr, Hall-Ursone S, Schlesinger LS, Alvarez X, Kaushal D, Giavedoni LD, Turner J, Martinez-Sobrido L, Torrelles JB. Oladunni FS, et al. Among authors: schlesinger ls. Nat Commun. 2020 Nov 30;11(1):6122. doi: 10.1038/s41467-020-19891-7. Nat Commun. 2020. PMID: 33257679 Free PMC article.
Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets.
Singh DK, Singh B, Ganatra SR, Gazi M, Cole J, Thippeshappa R, Alfson KJ, Clemmons E, Gonzalez O, Escobedo R, Lee TH, Chatterjee A, Goez-Gazi Y, Sharan R, Gough M, Alvarez C, Blakley A, Ferdin J, Bartley C, Staples H, Parodi L, Callery J, Mannino A, Klaffke B, Escareno P, Platt RN 2nd, Hodara V, Scordo J, Gautam S, Vilanova AG, Olmo-Fontanez A, Schami A, Oyejide A, Ajithdoss DK, Copin R, Baum A, Kyratsous C, Alvarez X, Ahmed M, Rosa B, Goodroe A, Dutton J, Hall-Ursone S, Frost PA, Voges AK, Ross CN, Sayers K, Chen C, Hallam C, Khader SA, Mitreva M, Anderson TJC, Martinez-Sobrido L, Patterson JL, Turner J, Torrelles JB, Dick EJ Jr, Brasky K, Schlesinger LS, Giavedoni LD, Carrion R Jr, Kaushal D. Singh DK, et al. Among authors: schlesinger ls. Nat Microbiol. 2021 Jan;6(1):73-86. doi: 10.1038/s41564-020-00841-4. Epub 2020 Dec 18. Nat Microbiol. 2021. PMID: 33340034 Free PMC article.
Author Correction: Responses to acute infection with SARS-CoV-2 in the lungs of rhesus macaques, baboons and marmosets.
Singh DK, Singh B, Ganatra SR, Gazi M, Cole J, Thippeshappa R, Alfson KJ, Clemmons E, Gonzalez O, Escobedo R, Lee TH, Chatterjee A, Goez-Gazi Y, Sharan R, Gough M, Alvarez C, Blakley A, Ferdin J, Bartley C, Staples H, Parodi L, Callery J, Mannino A, Klaffke B, Escareno P, Platt RN 2nd, Hodara V, Scordo J, Gautam S, Vilanova AG, Olmo-Fontanez A, Schami A, Oyejide A, Ajithdoss DK, Copin R, Baum A, Kyratsous C, Alvarez X, Ahmed M, Rosa B, Goodroe A, Dutton J, Hall-Ursone S, Frost PA, Voges AK, Ross CN, Sayers K, Chen C, Hallam C, Khader SA, Mitreva M, Anderson TJC, Martinez-Sobrido L, Patterson JL, Turner J, Torrelles JB, Dick EJ Jr, Brasky K, Schlesinger LS, Giavedoni LD, Carrion R Jr, Kaushal D. Singh DK, et al. Among authors: schlesinger ls. Nat Microbiol. 2021 Mar;6(3):413. doi: 10.1038/s41564-021-00867-2. Nat Microbiol. 2021. PMID: 33462437 Free PMC article. No abstract available.
IFN signaling and neutrophil degranulation transcriptional signatures are induced during SARS-CoV-2 infection.
Rosa BA, Ahmed M, Singh DK, Choreño-Parra JA, Cole J, Jiménez-Álvarez LA, Rodríguez-Reyna TS, Singh B, Gonzalez O, Carrion R Jr, Schlesinger LS, Martin J, Zúñiga J, Mitreva M, Kaushal D, Khader SA. Rosa BA, et al. Among authors: schlesinger ls. Commun Biol. 2021 Mar 5;4(1):290. doi: 10.1038/s42003-021-01829-4. Commun Biol. 2021. PMID: 33674719 Free PMC article.
Myeloid cell interferon responses correlate with clearance of SARS-CoV-2.
Singh DK, Aladyeva E, Das S, Singh B, Esaulova E, Swain A, Ahmed M, Cole J, Moodley C, Mehra S, Schlesinger LS, Artyomov MN, Khader SA, Kaushal D. Singh DK, et al. Among authors: schlesinger ls. Nat Commun. 2022 Feb 3;13(1):679. doi: 10.1038/s41467-022-28315-7. Nat Commun. 2022. PMID: 35115549 Free PMC article.
Isoniazid and rifapentine treatment effectively reduces persistent M. tuberculosis infection in macaque lungs.
Sharan R, Ganatra SR, Singh DK, Cole J, Foreman TW, Thippeshappa R, Peloquin CA, Shivanna V, Gonzalez O, Day CL, Gandhi NR, Dick EJ Jr, Hall-Ursone S, Mehra S, Schlesinger LS, Rengarajan J, Kaushal D. Sharan R, et al. Among authors: schlesinger ls. J Clin Invest. 2022 Sep 15;132(18):e161564. doi: 10.1172/JCI161564. J Clin Invest. 2022. PMID: 35862216 Free PMC article.
In Vitro Granuloma Models of Tuberculosis: Potential and Challenges.
Elkington P, Lerm M, Kapoor N, Mahon R, Pienaar E, Huh D, Kaushal D, Schlesinger LS. Elkington P, et al. Among authors: schlesinger ls. J Infect Dis. 2019 May 24;219(12):1858-1866. doi: 10.1093/infdis/jiz020. J Infect Dis. 2019. PMID: 30929010 Free PMC article. Review.
230 results