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A fruitful endeavor: modeling ALS in the fruit fly.
Casci I, Pandey UB. Casci I, et al. Among authors: pandey ub. Brain Res. 2015 May 14;1607:47-74. doi: 10.1016/j.brainres.2014.09.064. Epub 2014 Oct 5. Brain Res. 2015. PMID: 25289585 Free PMC article. Review.
Pur-alpha regulates cytoplasmic stress granule dynamics and ameliorates FUS toxicity.
Daigle JG, Krishnamurthy K, Ramesh N, Casci I, Monaghan J, McAvoy K, Godfrey EW, Daniel DC, Johnson EM, Monahan Z, Shewmaker F, Pasinelli P, Pandey UB. Daigle JG, et al. Among authors: pandey ub. Acta Neuropathol. 2016 Apr;131(4):605-20. doi: 10.1007/s00401-015-1530-0. Epub 2016 Jan 4. Acta Neuropathol. 2016. PMID: 26728149 Free PMC article.
Stress granules at the intersection of autophagy and ALS.
Monahan Z, Shewmaker F, Pandey UB. Monahan Z, et al. Among authors: pandey ub. Brain Res. 2016 Oct 15;1649(Pt B):189-200. doi: 10.1016/j.brainres.2016.05.022. Epub 2016 May 13. Brain Res. 2016. PMID: 27181519 Free PMC article. Review.
The chaperone HSPB8 reduces the accumulation of truncated TDP-43 species in cells and protects against TDP-43-mediated toxicity.
Crippa V, Cicardi ME, Ramesh N, Seguin SJ, Ganassi M, Bigi I, Diacci C, Zelotti E, Baratashvili M, Gregory JM, Dobson CM, Cereda C, Pandey UB, Poletti A, Carra S. Crippa V, et al. Among authors: pandey ub. Hum Mol Genet. 2016 Sep 15;25(18):3908-3924. doi: 10.1093/hmg/ddw232. Epub 2016 Jul 27. Hum Mol Genet. 2016. PMID: 27466192 Free PMC article.
Mutations in TGM6 induce the unfolded protein response in SCA35.
Tripathy D, Vignoli B, Ramesh N, Polanco MJ, Coutelier M, Stephen CD, Canossa M, Monin ML, Aeschlimann P, Turberville S, Aeschlimann D, Schmahmann JD, Hadjivassiliou M, Durr A, Pandey UB, Pennuto M, Basso M. Tripathy D, et al. Among authors: pandey ub. Hum Mol Genet. 2017 Oct 1;26(19):3749-3762. doi: 10.1093/hmg/ddx259. Hum Mol Genet. 2017. PMID: 28934387
RNP-Granule Assembly via Ataxin-2 Disordered Domains Is Required for Long-Term Memory and Neurodegeneration.
Bakthavachalu B, Huelsmeier J, Sudhakaran IP, Hillebrand J, Singh A, Petrauskas A, Thiagarajan D, Sankaranarayanan M, Mizoue L, Anderson EN, Pandey UB, Ross E, VijayRaghavan K, Parker R, Ramaswami M. Bakthavachalu B, et al. Among authors: pandey ub. Neuron. 2018 May 16;98(4):754-766.e4. doi: 10.1016/j.neuron.2018.04.032. Neuron. 2018. PMID: 29772202 Free article.
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