Goel S - Search Results

1

Safety and Clinical Activity of MEDI0562, a Humanized OX40 Agonist Monoclonal Antibody, in Adult Patients with Advanced Solid Tumors.

Glisson BS, Leidner RS, Ferris RL, Powderly J, Rizvi NA, Keam B, Schneider R, Goel S, Ohr JP, Burton J, Zheng Y, Eck S, Gribbin M, Streicher K, Townsley DM, Patel SP. Glisson BS, et al. Among authors: goel s. Clin Cancer Res. 2020 Oct 15;26(20):5358-5367. doi: 10.1158/1078-0432.CCR-19-3070. Epub 2020 Aug 14. Clin Cancer Res. 2020. PMID: 32816951 Clinical Trial.

2

Phase I clinical trial of irinotecan with oral capecitabine in patients with gastrointestinal and other solid malignancies.

Goel S, Jhawer M, Rajdev L, Hopkins U, Fehn K, Baker C, Chun HG, Makower D, Landau L, Hoffman A, Wadler S, Mani S. Goel S, et al. Am J Clin Oncol. 2002 Oct;25(5):528-34. doi: 10.1097/00000421-200210000-00022. Am J Clin Oncol. 2002. PMID: 12393999 Clinical Trial.

3

A safety study of a mixed-backbone oligonucleotide (GEM231) targeting the type I regulatory subunit alpha of protein kinase A using a continuous infusion schedule in patients with refractory solid tumors.

Goel S, Desai K, Bulgaru A, Fields A, Goldberg G, Agrawal S, Martin R, Grindel M, Mani S. Goel S, et al. Clin Cancer Res. 2003 Sep 15;9(11):4069-76. Clin Cancer Res. 2003. PMID: 14519628 Clinical Trial.

4

Pharmacokinetic and safety study of subcutaneously administered weekly ING-1, a human engineere monoclonal antibody targeting human EpCAM, in patients with advanced solid tumors.

Goel S, Bauer RJ, Desai K, Bulgaru A, Iqbal T, Strachan BK, Kim G, Kaubisch A, Vanhove GF, Goldberg G, Mani S. Goel S, et al. Ann Oncol. 2007 Oct;18(10):1704-7. doi: 10.1093/annonc/mdm280. Epub 2007 Aug 9. Ann Oncol. 2007. PMID: 17693421 Free article.

5

The effect of ketoconazole on the pharmacokinetics and pharmacodynamics of ixabepilone: a first in class epothilone B analogue in late-phase clinical development.

Goel S, Cohen M, Cömezoglu SN, Perrin L, André F, Jayabalan D, Iacono L, Comprelli A, Ly VT, Zhang D, Xu C, Humphreys WG, McDaid H, Goldberg G, Horwitz SB, Mani S. Goel S, et al. Clin Cancer Res. 2008 May 1;14(9):2701-9. doi: 10.1158/1078-0432.CCR-07-4151. Clin Cancer Res. 2008. PMID: 18451235 Clinical Trial.

6

A phase 1 open-label, accelerated dose-escalation study of the hypoxia-activated prodrug AQ4N in patients with advanced malignancies.

Papadopoulos KP, Goel S, Beeram M, Wong A, Desai K, Haigentz M, Milián ML, Mani S, Tolcher A, Lalani AS, Sarantopoulos J. Papadopoulos KP, et al. Among authors: goel s. Clin Cancer Res. 2008 Nov 1;14(21):7110-5. doi: 10.1158/1078-0432.CCR-08-0483. Clin Cancer Res. 2008. PMID: 18981010 Clinical Trial.

7

A phase I study of eribulin mesylate (E7389), a mechanistically novel inhibitor of microtubule dynamics, in patients with advanced solid malignancies.

Goel S, Mita AC, Mita M, Rowinsky EK, Chu QS, Wong N, Desjardins C, Fang F, Jansen M, Shuster DE, Mani S, Takimoto CH. Goel S, et al. Clin Cancer Res. 2009 Jun 15;15(12):4207-12. doi: 10.1158/1078-0432.CCR-08-2429. Epub 2009 Jun 9. Clin Cancer Res. 2009. PMID: 19509177 Clinical Trial.

8

Phase II study of paclitaxel plus the protein kinase C inhibitor bryostatin-1 in advanced pancreatic carcinoma.

Lam AP, Sparano JA, Vinciguerra V, Ocean AJ, Christos P, Hochster H, Camacho F, Goel S, Mani S, Kaubisch A. Lam AP, et al. Among authors: goel s. Am J Clin Oncol. 2010 Apr;33(2):121-4. doi: 10.1097/COC.0b013e3181a31920. Am J Clin Oncol. 2010. PMID: 19738452 Free PMC article. Clinical Trial.

9

Therapeutic oligonucleotides: the road not taken.

Stein CA, Goel S. Stein CA, et al. Among authors: goel s. Clin Cancer Res. 2011 Oct 15;17(20):6369-72. doi: 10.1158/1078-0432.CCR-11-2013. Epub 2011 Aug 23. Clin Cancer Res. 2011. PMID: 21862637

10

Safety, pharmacokinetics, and activity of EZN-2208, a novel conjugate of polyethylene glycol and SN38, in patients with advanced malignancies.

Kurzrock R, Goel S, Wheler J, Hong D, Fu S, Rezai K, Morgan-Linnell SK, Urien S, Mani S, Chaudhary I, Ghalib MH, Buchbinder A, Lokiec F, Mulcahy M. Kurzrock R, et al. Among authors: goel s. Cancer. 2012 Dec 15;118(24):6144-51. doi: 10.1002/cncr.27647. Epub 2012 Jun 6. Cancer. 2012. PMID: 22674635 Free article. Clinical Trial.

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