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Enhancer dependence of cell-type-specific gene expression increases with developmental age.
Cai W, Huang J, Zhu Q, Li BE, Seruggia D, Zhou P, Nguyen M, Fujiwara Y, Xie H, Yang Z, Hong D, Ren P, Xu J, Pu WT, Yuan GC, Orkin SH. Cai W, et al. Among authors: nguyen m. Proc Natl Acad Sci U S A. 2020 Sep 1;117(35):21450-21458. doi: 10.1073/pnas.2008672117. Epub 2020 Aug 19. Proc Natl Acad Sci U S A. 2020. PMID: 32817427 Free PMC article.
Strict in vivo specificity of the Bcl11a erythroid enhancer.
Smith EC, Luc S, Croney DM, Woodworth MB, Greig LC, Fujiwara Y, Nguyen M, Sher F, Macklis JD, Bauer DE, Orkin SH. Smith EC, et al. Among authors: nguyen m. Blood. 2016 Nov 10;128(19):2338-2342. doi: 10.1182/blood-2016-08-736249. Epub 2016 Oct 5. Blood. 2016. PMID: 27707736 Free PMC article.
Chronic Myelogenous Leukemia- Initiating Cells Require Polycomb Group Protein EZH2.
Xie H, Peng C, Huang J, Li BE, Kim W, Smith EC, Fujiwara Y, Qi J, Cheloni G, Das PP, Nguyen M, Li S, Bradner JE, Orkin SH. Xie H, et al. Among authors: nguyen m. Cancer Discov. 2016 Nov;6(11):1237-1247. doi: 10.1158/2159-8290.CD-15-1439. Epub 2016 Sep 14. Cancer Discov. 2016. PMID: 27630126 Free PMC article.
Distinct and combinatorial functions of Jmjd2b/Kdm4b and Jmjd2c/Kdm4c in mouse embryonic stem cell identity.
Das PP, Shao Z, Beyaz S, Apostolou E, Pinello L, De Los Angeles A, O'Brien K, Atsma JM, Fujiwara Y, Nguyen M, Ljuboja D, Guo G, Woo A, Yuan GC, Onder T, Daley G, Hochedlinger K, Kim J, Orkin SH. Das PP, et al. Among authors: nguyen m. Mol Cell. 2014 Jan 9;53(1):32-48. doi: 10.1016/j.molcel.2013.11.011. Epub 2013 Dec 19. Mol Cell. 2014. PMID: 24361252 Free PMC article.
Hematopoietic stem cells develop in the absence of endothelial cadherin 5 expression.
Anderson H, Patch TC, Reddy PN, Hagedorn EJ, Kim PG, Soltis KA, Chen MJ, Tamplin OJ, Frye M, MacLean GA, Hübner K, Bauer DE, Kanki JP, Vogin G, Huston NC, Nguyen M, Fujiwara Y, Paw BH, Vestweber D, Zon LI, Orkin SH, Daley GQ, Shah DI. Anderson H, et al. Among authors: nguyen m. Blood. 2015 Dec 24;126(26):2811-20. doi: 10.1182/blood-2015-07-659276. Epub 2015 Sep 18. Blood. 2015. PMID: 26385351 Free PMC article.
Failure to replicate the STAP cell phenomenon.
De Los Angeles A, Ferrari F, Fujiwara Y, Mathieu R, Lee S, Lee S, Tu HC, Ross S, Chou S, Nguyen M, Wu Z, Theunissen TW, Powell BE, Imsoonthornruksa S, Chen J, Borkent M, Krupalnik V, Lujan E, Wernig M, Hanna JH, Hochedlinger K, Pei D, Jaenisch R, Deng H, Orkin SH, Park PJ, Daley GQ. De Los Angeles A, et al. Among authors: nguyen m. Nature. 2015 Sep 24;525(7570):E6-9. doi: 10.1038/nature15513. Nature. 2015. PMID: 26399835 No abstract available.
Transcriptome Dynamics of Hematopoietic Stem Cell Formation Revealed Using a Combinatorial Runx1 and Ly6a Reporter System.
Chen MJ, Lummertz da Rocha E, Cahan P, Kubaczka C, Hunter P, Sousa P, Mullin NK, Fujiwara Y, Nguyen M, Tan Y, Landry S, Han A, Yang S, Lu YF, Jha DK, Vo LT, Zhou Y, North TE, Zon LI, Daley GQ, Schlaeger TM. Chen MJ, et al. Among authors: nguyen m. Stem Cell Reports. 2020 May 12;14(5):956-971. doi: 10.1016/j.stemcr.2020.03.020. Epub 2020 Apr 16. Stem Cell Reports. 2020. PMID: 32302558 Free PMC article.
6,824 results