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A high throughput screen for TMPRSS2 expression identifies FDA-approved and clinically advanced compounds that can limit SARS-CoV-2 entry.
Chen Y, Lear TB, Evankovich JW, Larsen MB, Lin B, Alfaras I, Kennerdell JR, Salminen L, Camarco DP, Lockwood KC, Liu J, Myerburg MM, McDyer JF, Liu Y, Finkel T, Chen BB. Chen Y, et al. Among authors: liu j, liu y. Res Sq [Preprint]. 2020 Aug 14:rs.3.rs-48659. doi: 10.21203/rs.3.rs-48659/v1. Res Sq. 2020. Update in: Nat Commun. 2021 Jun 23;12(1):3907. doi: 10.1038/s41467-021-24156-y PMID: 32818215 Free PMC article. Updated. Preprint.
Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation.
Evankovich J, Lear T, Mckelvey A, Dunn S, Londino J, Liu Y, Chen BB, Mallampalli RK. Evankovich J, et al. Among authors: liu y. FASEB J. 2017 Sep;31(9):3894-3903. doi: 10.1096/fj.201700031R. Epub 2017 May 17. FASEB J. 2017. PMID: 28515150 Free PMC article.
-Evankovich, J., Lear, T., Mckelvey, A., Dunn, S., Londino, J., Liu, Y., Chen, B. B., Mallampalli, R. K. Receptor for advanced glycation end products is targeted by FBXO10 for ubiquitination and degradation....
-Evankovich, J., Lear, T., Mckelvey, A., Dunn, S., Londino, J., Liu, Y., Chen, B. B., Mallampalli, R. K. Receptor for advanced …
KIAA0317 regulates pulmonary inflammation through SOCS2 degradation.
Lear TB, McKelvey AC, Evankovich JW, Rajbhandari S, Coon TA, Dunn SR, Londino JD, McVerry BJ, Zhang Y, Valenzi E, Burton CL, Gordon R, Gingras S, Lockwood KC, Jurczak MJ, Lafyatis R, Shlomchik MJ, Liu Y, Chen BB. Lear TB, et al. Among authors: liu y. JCI Insight. 2019 Oct 3;4(19):e129110. doi: 10.1172/jci.insight.129110. JCI Insight. 2019. PMID: 31578312 Free PMC article.
The RNFT2/IL-3Rα axis regulates IL-3 signaling and innate immunity.
Tong Y, Lear TB, Evankovich J, Chen Y, Londino JD, Myerburg MM, Zhang Y, Popescu ID, McDyer JF, McVerry BJ, Lockwood KC, Jurczak MJ, Liu Y, Chen BB. Tong Y, et al. Among authors: liu y. JCI Insight. 2020 Feb 13;5(3):e133652. doi: 10.1172/jci.insight.133652. JCI Insight. 2020. PMID: 31990690 Free PMC article.
Kelch-like protein 42 is a profibrotic ubiquitin E3 ligase involved in systemic sclerosis.
Lear TB, Lockwood KC, Larsen M, Tuncer F, Kennerdell JR, Morse C, Valenzi E, Tabib T, Jurczak MJ, Kass DJ, Evankovich JW, Finkel T, Lafyatis R, Liu Y, Chen BB. Lear TB, et al. Among authors: liu y. J Biol Chem. 2020 Mar 27;295(13):4171-4180. doi: 10.1074/jbc.AC119.012066. Epub 2020 Feb 17. J Biol Chem. 2020. PMID: 32071084 Free PMC article.
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