Huang M - Search Results

1

Small molecules targeting RORγt inhibit autoimmune disease by suppressing Th17 cell differentiation.

Tan J, Liu H, Huang M, Li N, Tang S, Meng J, Tang S, Zhou H, Kijlstra A, Yang P, Hou S. Tan J, et al. Among authors: huang m. Cell Death Dis. 2020 Aug 22;11(8):697. doi: 10.1038/s41419-020-02891-2. Cell Death Dis. 2020. PMID: 32829384 Free PMC article.

2

Intervention effect of gamma aminobutyric acid on anxiety behavior induced by phthalate (2-ethylhexyl ester) in rats.

Liu H, Guo Y, Yang T, Fan Z, Huang M, Liang S, Liu C. Liu H, et al. Among authors: huang m. Int J Neurosci. 2018 Oct;128(10):928-934. doi: 10.1080/00207454.2017.1405952. Epub 2018 Mar 20. Int J Neurosci. 2018. PMID: 29191066

3

Copper-catalyzed trifluoromethylation of trisubstituted allylic and homoallylic alcohols.

Lei J, Liu X, Zhang S, Jiang S, Huang M, Wu X, Zhu Q. Lei J, et al. Among authors: huang m. Chemistry. 2015 Apr 27;21(18):6700-3. doi: 10.1002/chem.201406627. Epub 2015 Mar 24. Chemistry. 2015. PMID: 25810003

4

Investigation of Covalent Warheads in the Design of 2-Aminopyrimidine-based FGFR4 Inhibitors.

Deng W, Chen X, Jiang K, Song X, Huang M, Tu ZC, Zhang Z, Lin X, Ortega R, Patterson AV, Smaill JB, Ding K, Chen S, Chen Y, Lu X. Deng W, et al. Among authors: huang m. ACS Med Chem Lett. 2021 Mar 22;12(4):647-652. doi: 10.1021/acsmedchemlett.1c00052. eCollection 2021 Apr 8. ACS Med Chem Lett. 2021. PMID: 33859803 Free PMC article.

5

Discovery of the First Examples of Threonine Tyrosine Kinase PROTAC Degraders.

Lu J, Huang Y, Huang J, He R, Huang M, Lu X, Xu Y, Zhou F, Zhang Z, Ding K. Lu J, et al. Among authors: huang m, huang j, huang y. J Med Chem. 2022 Feb 10;65(3):2313-2328. doi: 10.1021/acs.jmedchem.1c01768. Epub 2022 Jan 27. J Med Chem. 2022. PMID: 35084180

6

Pyrido[2, 3-d]pyrimidin-7(8H)-ones as new selective orally bioavailable Threonine Tyrosine Kinase (TTK) inhibitors.

Huang M, Huang Y, Guo J, Yu L, Chang Y, Wang X, Luo J, Huang Y, Tu Z, Lu X, Xu Y, Zhang Z, Zhang Z, Ding K. Huang M, et al. Among authors: huang y. Eur J Med Chem. 2021 Feb 5;211:113023. doi: 10.1016/j.ejmech.2020.113023. Epub 2020 Nov 16. Eur J Med Chem. 2021. PMID: 33248853

7

Design, Synthesis, and Structure-Activity Relationship Study of 2-Oxo-3,4-dihydropyrimido[4,5- d]pyrimidines as New Colony Stimulating Factor 1 Receptor (CSF1R) Kinase Inhibitors.

Xun Q, Zhang Z, Luo J, Tong L, Huang M, Wang Z, Zou J, Liu Y, Xu Y, Xie H, Tu ZC, Lu X, Ding K. Xun Q, et al. Among authors: huang m. J Med Chem. 2018 Mar 22;61(6):2353-2371. doi: 10.1021/acs.jmedchem.7b01612. Epub 2018 Mar 13. J Med Chem. 2018. PMID: 29499108

8

C3 ester side chain plays a pivotal role in the antitumor activity of Maytansinoids.

Li W, Huang M, Li Y, Xia A, Tan L, Zhang Z, Wang Y, Yang J. Li W, et al. Among authors: huang m. Biochem Biophys Res Commun. 2021 Aug 20;566:197-203. doi: 10.1016/j.bbrc.2021.05.071. Epub 2021 Jun 15. Biochem Biophys Res Commun. 2021. PMID: 34144258

9

Design and Optimization of 3'-(Imidazo[1,2-a]pyrazin-3-yl)-[1,1'-biphenyl]-3-carboxamides as Selective DDR1 Inhibitors.

Mo C, Zhang Z, Li Y, Huang M, Zou J, Luo J, Tu ZC, Xu Y, Ren X, Ding K, Lu X. Mo C, et al. Among authors: huang m. ACS Med Chem Lett. 2020 Jan 6;11(3):379-384. doi: 10.1021/acsmedchemlett.9b00495. eCollection 2020 Mar 12. ACS Med Chem Lett. 2020. PMID: 32184973 Free PMC article.

10

Structure-Based Ligand Discovery Targeting the Transmembrane Domain of Frizzled Receptor FZD7.

Li C, Wu Y, Wang W, Xu L, Zhou Y, Yue Y, Wu T, Yang M, Qiu Y, Huang M, Zhou F, Zhou Y, Hao P, Lin Z, Wang MW, Zhao S, Yang D, Xu F, Tao H. Li C, et al. Among authors: huang m. J Med Chem. 2023 Sep 14;66(17):11855-11868. doi: 10.1021/acs.jmedchem.2c01795. Epub 2023 Sep 5. J Med Chem. 2023. PMID: 37669317

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