Dai X - Search Results

1

Acetylation-dependent regulation of PD-L1 nuclear translocation dictates the efficacy of anti-PD-1 immunotherapy.

Gao Y, Nihira NT, Bu X, Chu C, Zhang J, Kolodziejczyk A, Fan Y, Chan NT, Ma L, Liu J, Wang D, Dai X, Liu H, Ono M, Nakanishi A, Inuzuka H, North BJ, Huang YH, Sharma S, Geng Y, Xu W, Liu XS, Li L, Miki Y, Sicinski P, Freeman GJ, Wei W. Gao Y, et al. Among authors: dai x. Nat Cell Biol. 2020 Sep;22(9):1064-1075. doi: 10.1038/s41556-020-0562-4. Epub 2020 Aug 24. Nat Cell Biol. 2020. PMID: 32839551 Free PMC article.

2

LATS suppresses mTORC1 activity to directly coordinate Hippo and mTORC1 pathways in growth control.

Gan W, Dai X, Dai X, Xie J, Yin S, Zhu J, Wang C, Liu Y, Guo J, Wang M, Liu J, Hu J, Quinton RJ, Ganem NJ, Liu P, Asara JM, Pandolfi PP, Yang Y, He Z, Gao G, Wei W. Gan W, et al. Among authors: dai x. Nat Cell Biol. 2020 Feb;22(2):246-256. doi: 10.1038/s41556-020-0463-6. Epub 2020 Feb 3. Nat Cell Biol. 2020. PMID: 32015438 Free PMC article.

3

DUB-independent regulation of pVHL by OTUD6B suppresses hepatocellular carcinoma.

Dai X, Liu J, Wei W. Dai X, et al. Protein Cell. 2020 Aug;11(8):546-548. doi: 10.1007/s13238-020-00721-x. Protein Cell. 2020. PMID: 32323143 Free PMC article. Review. No abstract available.

4

The diverse roles of SPOP in prostate cancer and kidney cancer.

Wang Z, Song Y, Ye M, Dai X, Zhu X, Wei W. Wang Z, et al. Among authors: dai x. Nat Rev Urol. 2020 Jun;17(6):339-350. doi: 10.1038/s41585-020-0314-z. Epub 2020 Apr 30. Nat Rev Urol. 2020. PMID: 32355326 Review.

5

RBR E3 ubiquitin ligases in tumorigenesis.

Wang P, Dai X, Jiang W, Li Y, Wei W. Wang P, et al. Among authors: dai x. Semin Cancer Biol. 2020 Dec;67(Pt 2):131-144. doi: 10.1016/j.semcancer.2020.05.002. Epub 2020 May 19. Semin Cancer Biol. 2020. PMID: 32442483 Review.

6

Post-translational regulations of PD-L1 and PD-1: Mechanisms and opportunities for combined immunotherapy.

Dai X, Gao Y, Wei W. Dai X, et al. Semin Cancer Biol. 2022 Oct;85:246-252. doi: 10.1016/j.semcancer.2021.04.002. Epub 2021 Apr 5. Semin Cancer Biol. 2022. PMID: 33831533 Free PMC article. Review.

7

Energy status dictates PD-L1 protein abundance and anti-tumor immunity to enable checkpoint blockade.

Dai X, Bu X, Gao Y, Guo J, Hu J, Jiang C, Zhang Z, Xu K, Duan J, He S, Zhang J, Wan L, Liu T, Zhou X, Hung MC, Freeman GJ, Wei W. Dai X, et al. Mol Cell. 2021 Jun 3;81(11):2317-2331.e6. doi: 10.1016/j.molcel.2021.03.037. Epub 2021 Apr 27. Mol Cell. 2021. PMID: 33909988 Free PMC article.

8

DNA-PK promotes activation of the survival kinase AKT in response to DNA damage through an mTORC2-ECT2 pathway.

Liu L, Dai X, Yin S, Liu P, Hill EG, Wei W, Gan W. Liu L, et al. Among authors: dai x. Sci Signal. 2022 Jan 4;15(715):eabh2290. doi: 10.1126/scisignal.abh2290. Epub 2022 Jan 4. Sci Signal. 2022. PMID: 34982576 Free PMC article.

9

S6K1-mediated phosphorylation of PDK1 impairs AKT kinase activity and oncogenic functions.

Jiang Q, Zhang X, Dai X, Han S, Wu X, Wang L, Wei W, Zhang N, Xie W, Guo J. Jiang Q, et al. Among authors: dai x. Nat Commun. 2022 Mar 22;13(1):1548. doi: 10.1038/s41467-022-28910-8. Nat Commun. 2022. PMID: 35318320 Free PMC article.

10

Ring domains are essential for GATOR2-dependent mTORC1 activation.

Jiang C, Dai X, He S, Zhou H, Fang L, Guo J, Liu S, Zhang T, Pan W, Yu H, Fu T, Li D, Inuzuka H, Wang P, Xiao J, Wei W. Jiang C, et al. Among authors: dai x. Mol Cell. 2023 Jan 5;83(1):74-89.e9. doi: 10.1016/j.molcel.2022.11.021. Epub 2022 Dec 16. Mol Cell. 2023. PMID: 36528027 Free PMC article.

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