Pflimlin E - Search Results

1

Engineering of a Potent, Long-Acting NPY2R Agonist for Combination with a GLP-1R Agonist as a Multi-Hormonal Treatment for Obesity.

Lear S, Pflimlin E, Zhou Z, Huang D, Weng S, Nguyen-Tran V, Joseph SB, Roller S, Peterson S, Li J, Tremblay M, Schultz PG, Shen W. Lear S, et al. Among authors: pflimlin e. J Med Chem. 2020 Sep 10;63(17):9660-9671. doi: 10.1021/acs.jmedchem.0c00740. Epub 2020 Aug 26. J Med Chem. 2020. PMID: 32844654

2

Engineering a Potent, Long-Acting, and Periphery-Restricted Oxytocin Receptor Agonist with Anorexigenic and Body Weight Reducing Effects.

Pflimlin E, Zhou Z, Amso Z, Fu Q, Lee C, Muppiddi A, Joseph SB, Nguyen-Tran V, Shen W. Pflimlin E, et al. J Med Chem. 2020 Jan 9;63(1):382-390. doi: 10.1021/acs.jmedchem.9b01862. Epub 2019 Dec 18. J Med Chem. 2020. PMID: 31850759

3

Design of a Long-Acting and Selective MEG-Fatty Acid Stapled Prolactin-Releasing Peptide Analog.

Pflimlin E, Lear S, Lee C, Yu S, Zou H, To A, Joseph S, Nguyen-Tran V, Tremblay MS, Shen W. Pflimlin E, et al. ACS Med Chem Lett. 2019 Jul 5;10(8):1166-1172. doi: 10.1021/acsmedchemlett.9b00182. eCollection 2019 Aug 8. ACS Med Chem Lett. 2019. PMID: 31413801 Free PMC article.

4

Design and Synthesis of Potent, Long-Acting Lipidated Relaxin-2 Analogs.

Muppidi A, Lee SJ, Hsu CH, Zou H, Lee C, Pflimlin E, Mahankali M, Yang P, Chao E, Ahmad I, Crameri A, Wang D, Woods A, Shen W. Muppidi A, et al. Among authors: pflimlin e. Bioconjug Chem. 2019 Jan 16;30(1):83-89. doi: 10.1021/acs.bioconjchem.8b00764. Epub 2018 Dec 13. Bioconjug Chem. 2019. PMID: 30543420

5

Molecular interaction site on procoagulant myosin for factor Xa-dependent prothrombin activation.

Deguchi H, Guo Z, Hayat M, Pflimlin E, Lear S, Shen W, Griffin JH. Deguchi H, et al. Among authors: pflimlin e. J Biol Chem. 2019 Oct 11;294(41):15176-15181. doi: 10.1074/jbc.AC119.010236. Epub 2019 Sep 3. J Biol Chem. 2019. PMID: 31481465 Free PMC article.

6

LIT-001, the First Nonpeptide Oxytocin Receptor Agonist that Improves Social Interaction in a Mouse Model of Autism.

Frantz MC, Pellissier LP, Pflimlin E, Loison S, Gandía J, Marsol C, Durroux T, Mouillac B, Becker JAJ, Le Merrer J, Valencia C, Villa P, Bonnet D, Hibert M. Frantz MC, et al. Among authors: pflimlin e. J Med Chem. 2018 Oct 11;61(19):8670-8692. doi: 10.1021/acs.jmedchem.8b00697. Epub 2018 Sep 24. J Med Chem. 2018. PMID: 30199637

7

Syntheses of Morpholine-Based Nucleotide Analogs for Hepatic siRNA Targeting and Stabilization.

Hofmeister A, Jahn-Hofmann K, Brunner B, Helms MW, Metz-Weidmann C, Krack A, Kurz M, Li Z, Weitzenberg MM, Pflimlin E, Plettenburg O, Scheidler S. Hofmeister A, et al. Among authors: pflimlin e. J Med Chem. 2021 May 27;64(10):6838-6855. doi: 10.1021/acs.jmedchem.1c00144. Epub 2021 May 5. J Med Chem. 2021. PMID: 33950677

8

Selective nonpeptidic fluorescent ligands for oxytocin receptor: design, synthesis, and application to time-resolved FRET binding assay.

Karpenko IA, Margathe JF, Rodriguez T, Pflimlin E, Dupuis E, Hibert M, Durroux T, Bonnet D. Karpenko IA, et al. Among authors: pflimlin e. J Med Chem. 2015 Mar 12;58(5):2547-52. doi: 10.1021/jm501395b. Epub 2015 Feb 12. J Med Chem. 2015. PMID: 25642985

9

Combinatorial aid for underprivileged scaffolds: solution and solid-phase strategies for a rapid and efficient access to novel aza-diketopiperazines (Aza-DKP).

Bonnet D, Margathe JF, Radford S, Pflimlin E, Riché S, Doman P, Hibert M, Ganesan A. Bonnet D, et al. Among authors: pflimlin e. ACS Comb Sci. 2012 May 14;14(5):323-34. doi: 10.1021/co300015k. Epub 2012 Apr 6. ACS Comb Sci. 2012. PMID: 22458603

10

Evaluation of a solid-supported tagging strategy for mass spectrometric analysis of peptides.

Hudson SR, Chadbourne FL, Helliwell PA, Pflimlin E, Thomas-Oates JE, Routledge A. Hudson SR, et al. Among authors: pflimlin e. ACS Comb Sci. 2012 Feb 13;14(2):97-100. doi: 10.1021/co2000899. Epub 2012 Jan 20. ACS Comb Sci. 2012. PMID: 22220996

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