Posner GH - Search Results

1

Artemisinins target the intermediate filament protein vimentin for human cytomegalovirus inhibition.

Roy S, Kapoor A, Zhu F, Mukhopadhyay R, Ghosh AK, Lee H, Mazzone J, Posner GH, Arav-Boger R. Roy S, et al. Among authors: posner gh. J Biol Chem. 2020 Oct 30;295(44):15013-15028. doi: 10.1074/jbc.RA120.014116. Epub 2020 Aug 27. J Biol Chem. 2020. PMID: 32855235 Free PMC article.

2

Artemisinin-derived dimer diphenyl phosphate is an irreversible inhibitor of human cytomegalovirus replication.

He R, Park K, Cai H, Kapoor A, Forman M, Mott B, Posner GH, Arav-Boger R. He R, et al. Among authors: posner gh. Antimicrob Agents Chemother. 2012 Jul;56(7):3508-15. doi: 10.1128/AAC.00519-12. Epub 2012 Apr 30. Antimicrob Agents Chemother. 2012. PMID: 22547612 Free PMC article.

3

Inhibition of human cytomegalovirus replication by artemisinins: effects mediated through cell cycle modulation.

Roy S, He R, Kapoor A, Forman M, Mazzone JR, Posner GH, Arav-Boger R. Roy S, et al. Among authors: posner gh. Antimicrob Agents Chemother. 2015 Jul;59(7):3870-9. doi: 10.1128/AAC.00262-15. Epub 2015 Apr 13. Antimicrob Agents Chemother. 2015. PMID: 25870074 Free PMC article.

4

Artemisinin-derived dimers have greatly improved anti-cytomegalovirus activity compared to artemisinin monomers.

Arav-Boger R, He R, Chiou CJ, Liu J, Woodard L, Rosenthal A, Jones-Brando L, Forman M, Posner G. Arav-Boger R, et al. PLoS One. 2010 Apr 28;5(4):e10370. doi: 10.1371/journal.pone.0010370. PLoS One. 2010. PMID: 20442781 Free PMC article.

5

An artemisinin-derived dimer has highly potent anti-cytomegalovirus (CMV) and anti-cancer activities.

He R, Mott BT, Rosenthal AS, Genna DT, Posner GH, Arav-Boger R. He R, et al. Among authors: posner gh. PLoS One. 2011;6(8):e24334. doi: 10.1371/journal.pone.0024334. Epub 2011 Aug 31. PLoS One. 2011. PMID: 21904628 Free PMC article.

6

Artemisinin-derived dimer phosphate esters as potent anti-cytomegalovirus (anti-CMV) and anti-cancer agents: a structure-activity study.

Mott BT, He R, Chen X, Fox JM, Civin CI, Arav-Boger R, Posner GH. Mott BT, et al. Among authors: posner gh. Bioorg Med Chem. 2013 Jul 1;21(13):3702-7. doi: 10.1016/j.bmc.2013.04.027. Epub 2013 Apr 22. Bioorg Med Chem. 2013. PMID: 23673218 Free PMC article.

7

Unique and highly selective anticytomegalovirus activities of artemisinin-derived dimer diphenyl phosphate stem from combination of dimer unit and a diphenyl phosphate moiety.

He R, Forman M, Mott BT, Venkatadri R, Posner GH, Arav-Boger R. He R, et al. Among authors: posner gh. Antimicrob Agents Chemother. 2013 Sep;57(9):4208-14. doi: 10.1128/AAC.00893-13. Epub 2013 Jun 17. Antimicrob Agents Chemother. 2013. PMID: 23774439 Free PMC article.

8

In vitro combination of anti-cytomegalovirus compounds acting through different targets: role of the slope parameter and insights into mechanisms of Action.

Cai H, Kapoor A, He R, Venkatadri R, Forman M, Posner GH, Arav-Boger R. Cai H, et al. Among authors: posner gh. Antimicrob Agents Chemother. 2014;58(2):986-94. doi: 10.1128/AAC.01972-13. Epub 2013 Nov 25. Antimicrob Agents Chemother. 2014. PMID: 24277030 Free PMC article.

9

Artemisinin-derived dimer ART-838 potently inhibited human acute leukemias, persisted in vivo, and synergized with antileukemic drugs.

Fox JM, Moynihan JR, Mott BT, Mazzone JR, Anders NM, Brown PA, Rudek MA, Liu JO, Arav-Boger R, Posner GH, Civin CI, Chen X. Fox JM, et al. Among authors: posner gh. Oncotarget. 2016 Feb 9;7(6):7268-79. doi: 10.18632/oncotarget.6896. Oncotarget. 2016. PMID: 26771236 Free PMC article.

10

Recombinant luciferase-expressing human cytomegalovirus (CMV) for evaluation of CMV inhibitors.

He R, Sandford G, Hayward GS, Burns WH, Posner GH, Forman M, Arav-Boger R. He R, et al. Among authors: posner gh. Virol J. 2011 Jan 26;8:40. doi: 10.1186/1743-422X-8-40. Virol J. 2011. PMID: 21269468 Free PMC article.

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