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Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency.
Zhang J, Velmeshev D, Hashimoto K, Huang YH, Hofmann JW, Shi X, Chen J, Leidal AM, Dishart JG, Cahill MK, Kelley KW, Liddelow SA, Seeley WW, Miller BL, Walther TC, Farese RV Jr, Taylor JP, Ullian EM, Huang B, Debnath J, Wittmann T, Kriegstein AR, Huang EJ. Zhang J, et al. Among authors: leidal am. Nature. 2020 Dec;588(7838):459-465. doi: 10.1038/s41586-020-2709-7. Epub 2020 Aug 31. Nature. 2020. PMID: 32866962 Free PMC article.
NBR1 enables autophagy-dependent focal adhesion turnover.
Kenific CM, Stehbens SJ, Goldsmith J, Leidal AM, Faure N, Ye J, Wittmann T, Debnath J. Kenific CM, et al. Among authors: leidal am. J Cell Biol. 2016 Feb 29;212(5):577-90. doi: 10.1083/jcb.201503075. Epub 2016 Feb 22. J Cell Biol. 2016. PMID: 26903539 Free PMC article.
A computationally engineered RAS rheostat reveals RAS-ERK signaling dynamics.
Rose JC, Huang PS, Camp ND, Ye J, Leidal AM, Goreshnik I, Trevillian BM, Dickinson MS, Cunningham-Bryant D, Debnath J, Baker D, Wolf-Yadlin A, Maly DJ. Rose JC, et al. Among authors: leidal am. Nat Chem Biol. 2017 Jan;13(1):119-126. doi: 10.1038/nchembio.2244. Epub 2016 Nov 21. Nat Chem Biol. 2017. PMID: 27870838 Free PMC article.
Autophagy and the cell biology of age-related disease.
Leidal AM, Levine B, Debnath J. Leidal AM, et al. Nat Cell Biol. 2018 Dec;20(12):1338-1348. doi: 10.1038/s41556-018-0235-8. Epub 2018 Nov 26. Nat Cell Biol. 2018. PMID: 30482941 Review.
33 results