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The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies.
Kumagai S, Togashi Y, Kamada T, Sugiyama E, Nishinakamura H, Takeuchi Y, Vitaly K, Itahashi K, Maeda Y, Matsui S, Shibahara T, Yamashita Y, Irie T, Tsuge A, Fukuoka S, Kawazoe A, Udagawa H, Kirita K, Aokage K, Ishii G, Kuwata T, Nakama K, Kawazu M, Ueno T, Yamazaki N, Goto K, Tsuboi M, Mano H, Doi T, Shitara K, Nishikawa H. Kumagai S, et al. Among authors: nishikawa h. Nat Immunol. 2020 Nov;21(11):1346-1358. doi: 10.1038/s41590-020-0769-3. Epub 2020 Aug 31. Nat Immunol. 2020. PMID: 32868929
Regulatory T cells in tumor immunity.
Nishikawa H, Sakaguchi S. Nishikawa H, et al. Int J Cancer. 2010 Aug 15;127(4):759-67. doi: 10.1002/ijc.25429. Int J Cancer. 2010. PMID: 20518016 Review.
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+ regulatory T cells, evoking antitumor immune responses in humans.
Sugiyama D, Nishikawa H, Maeda Y, Nishioka M, Tanemura A, Katayama I, Ezoe S, Kanakura Y, Sato E, Fukumori Y, Karbach J, Jäger E, Sakaguchi S. Sugiyama D, et al. Among authors: nishikawa h. Proc Natl Acad Sci U S A. 2013 Oct 29;110(44):17945-50. doi: 10.1073/pnas.1316796110. Epub 2013 Oct 14. Proc Natl Acad Sci U S A. 2013. PMID: 24127572 Free PMC article.
Regulatory T cells in cancer immunotherapy.
Nishikawa H, Sakaguchi S. Nishikawa H, et al. Curr Opin Immunol. 2014 Apr;27:1-7. doi: 10.1016/j.coi.2013.12.005. Epub 2014 Jan 14. Curr Opin Immunol. 2014. PMID: 24413387 Review.
Regulatory T cells in cancer; can they be controlled?
Adeegbe DO, Nishikawa H. Adeegbe DO, et al. Among authors: nishikawa h. Immunotherapy. 2015;7(8):843-6. doi: 10.2217/imt.15.52. Epub 2015 Aug 28. Immunotherapy. 2015. PMID: 26316166 No abstract available.
1,601 results