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A simplified cell-based assay to identify coronavirus 3CL protease inhibitors.
Resnick SJ, Iketani S, Hong SJ, Zask A, Liu H, Kim S, Melore S, Nair MS, Huang Y, Tay NES, Rovis T, Yang HW, Stockwell BR, Ho DD, Chavez A. Resnick SJ, et al. Among authors: ho dd. bioRxiv [Preprint]. 2020 Aug 29:2020.08.29.272864. doi: 10.1101/2020.08.29.272864. bioRxiv. 2020. PMID: 32869020 Free PMC article. Preprint.
The HIV-1 vaccine race.
Ho DD, Huang Y. Ho DD, et al. Cell. 2002 Jul 26;110(2):135-8. doi: 10.1016/s0092-8674(02)00832-2. Cell. 2002. PMID: 12150921 Free article. Review.
Potent Neutralizing Antibodies Directed to Multiple Epitopes on SARS-CoV-2 Spike.
Liu L, Wang P, Nair MS, Yu J, Rapp M, Wang Q, Luo Y, Chan JF, Sahi V, Figueroa A, Guo XV, Cerutti G, Bimela J, Gorman J, Zhou T, Chen Z, Yuen KY, Kwong PD, Sodroski JG, Yin MT, Sheng Z, Huang Y, Shapiro L, Ho DD. Liu L, et al. Among authors: ho dd. bioRxiv [Preprint]. 2020 Jul 16:2020.06.17.153486. doi: 10.1101/2020.06.17.153486. bioRxiv. 2020. Update in: Nature. 2020 Aug;584(7821):450-456. doi: 10.1038/s41586-020-2571-7 PMID: 32587975 Free PMC article. Updated. Preprint.
Paired heavy and light chain signatures contribute to potent SARS-CoV-2 neutralization in public antibody responses.
Banach BB, Cerutti G, Fahad AS, Shen CH, de Souza MO, Katsamba PS, Tsybovsky Y, Wang P, Nair MS, Huang Y, Urdániz IMF, Steiner PJ, Gutiérrez-González M, Liu L, López Acevedo SN, Nazzari A, Wolfe JR, Luo Y, Olia AS, Teng IT, Yu J, Zhou T, Reddem ER, Bimela J, Pan X, Madan B, Laflin AD, Nimrania R, Yuen KT, Whitehead TA, Ho DD, Kwong PD, Shapiro L, DeKosky BJ. Banach BB, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Jan 3:2020.12.31.424987. doi: 10.1101/2020.12.31.424987. bioRxiv. 2021. Update in: Cell Rep. 2021 Oct 5;37(1):109771. doi: 10.1016/j.celrep.2021.109771 PMID: 33442681 Free PMC article. Updated. Preprint.
Antibody Resistance of SARS-CoV-2 Variants B.1.351 and B.1.1.7.
Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yin MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD. Wang P, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Feb 12:2021.01.25.428137. doi: 10.1101/2021.01.25.428137. bioRxiv. 2021. Update in: Nature. 2021 May;593(7857):130-135. doi: 10.1038/s41586-021-03398-2 PMID: 33532778 Free PMC article. Updated. Preprint.
Structural Basis for Accommodation of Emerging B.1.351 and B.1.1.7 Variants by Two Potent SARS-CoV-2 Neutralizing Antibodies.
Cerutti G, Rapp M, Guo Y, Bahna F, Bimela J, Reddem ER, Yu J, Wang P, Liu L, Huang Y, Ho DD, Kwong PD, Sheng Z, Shapiro L. Cerutti G, et al. Among authors: ho dd. bioRxiv [Preprint]. 2021 Feb 22:2021.02.21.432168. doi: 10.1101/2021.02.21.432168. bioRxiv. 2021. Update in: Structure. 2021 Jul 1;29(7):655-663.e4. doi: 10.1016/j.str.2021.05.014 PMID: 33655245 Free PMC article. Updated. Preprint.
Antibody resistance of SARS-CoV-2 variants B.1.351 and B.1.1.7.
Wang P, Nair MS, Liu L, Iketani S, Luo Y, Guo Y, Wang M, Yu J, Zhang B, Kwong PD, Graham BS, Mascola JR, Chang JY, Yin MT, Sobieszczyk M, Kyratsous CA, Shapiro L, Sheng Z, Huang Y, Ho DD. Wang P, et al. Among authors: ho dd. Nature. 2021 May;593(7857):130-135. doi: 10.1038/s41586-021-03398-2. Epub 2021 Mar 8. Nature. 2021. PMID: 33684923
Lead compounds for the development of SARS-CoV-2 3CL protease inhibitors.
Iketani S, Forouhar F, Liu H, Hong SJ, Lin FY, Nair MS, Zask A, Huang Y, Xing L, Stockwell BR, Chavez A, Ho DD. Iketani S, et al. Among authors: ho dd. Nat Commun. 2021 Apr 1;12(1):2016. doi: 10.1038/s41467-021-22362-2. Nat Commun. 2021. PMID: 33795671 Free PMC article.
464 results