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118 results

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Page 1
Mavacamten for treatment of symptomatic obstructive hypertrophic cardiomyopathy (EXPLORER-HCM): a randomised, double-blind, placebo-controlled, phase 3 trial.
Olivotto I, Oreziak A, Barriales-Villa R, Abraham TP, Masri A, Garcia-Pavia P, Saberi S, Lakdawala NK, Wheeler MT, Owens A, Kubanek M, Wojakowski W, Jensen MK, Gimeno-Blanes J, Afshar K, Myers J, Hegde SM, Solomon SD, Sehnert AJ, Zhang D, Li W, Bhattacharya M, Edelberg JM, Waldman CB, Lester SJ, Wang A, Ho CY, Jacoby D; EXPLORER-HCM study investigators. Olivotto I, et al. Among authors: lakdawala nk. Lancet. 2020 Sep 12;396(10253):759-769. doi: 10.1016/S0140-6736(20)31792-X. Epub 2020 Aug 29. Lancet. 2020. PMID: 32871100 Clinical Trial.
Plain Language Summary of Publication of the safety and efficacy of ARRY-371797 in people with dilated cardiomyopathy and a faulty LMNA gene.
MacRae CA, Taylor MR, Mestroni L, Moses J, Ashley EA, Wheeler MT, Lakdawala NK, Hershberger RE, Sandor V, Saunders ME, Oliver C, Lee PA, Judge DP. MacRae CA, et al. Among authors: lakdawala nk. Future Cardiol. 2023 Feb;19(2):55-63. doi: 10.2217/fca-2022-0099. Epub 2023 Jan 31. Future Cardiol. 2023. PMID: 36718638 Free article. Review.
Long-term effect of mavacamten in obstructive hypertrophic cardiomyopathy.
Garcia-Pavia P, Oręziak A, Masri A, Barriales-Villa R, Abraham TP, Owens AT, Jensen MK, Wojakowski W, Seidler T, Hagege A, Lakdawala NK, Wang A, Wheeler MT, Choudhury L, Balaratnam G, Shah A, Fox S, Hegde SM, Olivotto I. Garcia-Pavia P, et al. Among authors: lakdawala nk. Eur Heart J. 2024 Dec 16;45(47):5071-5083. doi: 10.1093/eurheartj/ehae579. Eur Heart J. 2024. PMID: 39217450 Free PMC article.
Mavacamten-Associated Temporal Changes in Left Atrial Function in Obstructive HCM: Insights From the VALOR-HCM Trial.
Desai MY, Okushi Y, Wolski K, Geske JB, Owens A, Saberi S, Wang A, Cremer PC, Sherrid M, Lakdawala NK, Tower-Rader A, Fermin D, Naidu SS, Lampl KL, Sehnert AJ, Nissen SE, Popovic ZB; VALOR-HCM Investigators. Desai MY, et al. Among authors: lakdawala nk. JACC Cardiovasc Imaging. 2024 Sep 2:S1936-878X(24)00345-0. doi: 10.1016/j.jcmg.2024.08.005. Online ahead of print. JACC Cardiovasc Imaging. 2024. PMID: 39254622 Free article.
Stop Dreaming: Mavacamten REMS Data Are Here.
Masri A, Lakdawala NK. Masri A, et al. Among authors: lakdawala nk. Circ Heart Fail. 2024 Nov 11. doi: 10.1161/CIRCHEARTFAILURE.124.012545. Online ahead of print. Circ Heart Fail. 2024. PMID: 39523953 Free article. No abstract available.
Limited Concordance of Left Ventricular Ejection Fraction and Chamber Dimensions with Automated Assessments in Hypertrophic Cardiomyopathy: A Sub-study from VALOR-HCM.
Parizher G, Haouzi A, Jaber WA, Owens A, Wolski K, Geske JB, Saberi S, Wang A, Sherrid M, Lakdawala NK, Tower-Rader A, Fermin D, Naidu SS, Popovic ZB, Smedira NG, Schaff H, McErlean E, Sewell C, Lampl K, Sehnert AJ, Nissen SE, Desai MY, Cremer PC. Parizher G, et al. Among authors: lakdawala nk. J Am Soc Echocardiogr. 2024 Dec 27:S0894-7317(24)00648-5. doi: 10.1016/j.echo.2024.12.009. Online ahead of print. J Am Soc Echocardiogr. 2024. PMID: 39733991 No abstract available.
Endpoint Selection in Randomized Clinical Trials for Hypertrophic Cardiomyopathy.
Aimo A, Olivotto I, Todiere G, Barison A, Panichella G, Fiuzat M, Linde C, Lakdawala NK, Desai M, Zannad F, Maron MS. Aimo A, et al. Among authors: lakdawala nk. JACC Heart Fail. 2024 Dec 7:S2213-1779(24)00805-9. doi: 10.1016/j.jchf.2024.10.016. Online ahead of print. JACC Heart Fail. 2024. PMID: 39708028 Review.
Association Between age or Duration of Diagnosis in Obstructive Hypertrophic Cardiomyopathy and Response to Mavacamten Treatment: Exploratory Analysis of the EXPLORER-HCM Trial.
Wang A, Lakdawala NK, Abraham TP, Nilles EK, Wojdyla DM, Owens AT, Bach RG, Saberi S, Sehnert A, Cresci S. Wang A, et al. Among authors: lakdawala nk. J Card Fail. 2024 Dec 7:S1071-9164(24)00963-1. doi: 10.1016/j.cardfail.2024.10.449. Online ahead of print. J Card Fail. 2024. PMID: 39653325
Mavacamten in Patients With Hypertrophic Cardiomyopathy Referred for Septal Reduction: Week 128 Results from VALOR-HCM.
Desai MY, Wolski K, Owens A, Geske JB, Saberi S, Wang A, Sherrid M, Cremer PC, Lakdawala NK, Tower-Rader A, Fermin D, Naidu SS, Smedira NG, Schaff H, Gong Z, Mudarris L, Lampl K, Sehnert AJ, Nissen SE; VALOR-HCM investigators. Desai MY, et al. Among authors: lakdawala nk. Circulation. 2024 Nov 18. doi: 10.1161/CIRCULATIONAHA.124.072445. Online ahead of print. Circulation. 2024. PMID: 39556124 Free article.
118 results