Tomlinson IPM - Search Results

1

Pervasive chromosomal instability and karyotype order in tumour evolution.

Watkins TBK, Lim EL, Petkovic M, Elizalde S, Birkbak NJ, Wilson GA, Moore DA, Grönroos E, Rowan A, Dewhurst SM, Demeulemeester J, Dentro SC, Horswell S, Au L, Haase K, Escudero M, Rosenthal R, Bakir MA, Xu H, Litchfield K, Lu WT, Mourikis TP, Dietzen M, Spain L, Cresswell GD, Biswas D, Lamy P, Nordentoft I, Harbst K, Castro-Giner F, Yates LR, Caramia F, Jaulin F, Vicier C, Tomlinson IPM, Brastianos PK, Cho RJ, Bastian BC, Dyrskjøt L, Jönsson GB, Savas P, Loi S, Campbell PJ, Andre F, Luscombe NM, Steeghs N, Tjan-Heijnen VCG, Szallasi Z, Turajlic S, Jamal-Hanjani M, Van Loo P, Bakhoum SF, Schwarz RF, McGranahan N, Swanton C. Watkins TBK, et al. Among authors: tomlinson ipm. Nature. 2020 Nov;587(7832):126-132. doi: 10.1038/s41586-020-2698-6. Epub 2020 Sep 2. Nature. 2020. PMID: 32879494 Free PMC article.

2

Mutations in Bcl10 are very rare in colorectal cancer.

Stone JG, Rowan AJ, Tomlinson IP, Houlston RS. Stone JG, et al. Br J Cancer. 1999 Jul;80(10):1569-70. doi: 10.1038/sj.bjc.6690562. Br J Cancer. 1999. PMID: 10408399 Free PMC article.

3

SMAD4 mutations in colorectal cancer probably occur before chromosomal instability, but after divergence of the microsatellite instability pathway.

Woodford-Richens KL, Rowan AJ, Gorman P, Halford S, Bicknell DC, Wasan HS, Roylance RR, Bodmer WF, Tomlinson IP. Woodford-Richens KL, et al. Proc Natl Acad Sci U S A. 2001 Aug 14;98(17):9719-23. doi: 10.1073/pnas.171321498. Epub 2001 Jul 31. Proc Natl Acad Sci U S A. 2001. PMID: 11481457 Free PMC article.

4

Low-level microsatellite instability occurs in most colorectal cancers and is a nonrandomly distributed quantitative trait.

Halford S, Sasieni P, Rowan A, Wasan H, Bodmer W, Talbot I, Hawkins N, Ward R, Tomlinson I. Halford S, et al. Cancer Res. 2002 Jan 1;62(1):53-7. Cancer Res. 2002. PMID: 11782358

5

The Wnt pathway, epithelial-stromal interactions, and malignant progression in phyllodes tumours.

Sawyer EJ, Hanby AM, Rowan AJ, Gillett CE, Thomas RE, Poulsom R, Lakhani SR, Ellis IO, Ellis P, Tomlinson IP. Sawyer EJ, et al. J Pathol. 2002 Apr;196(4):437-44. doi: 10.1002/path.1067. J Pathol. 2002. PMID: 11920740

6

Array comparative genomic hybridization analysis of colorectal cancer cell lines and primary carcinomas.

Douglas EJ, Fiegler H, Rowan A, Halford S, Bicknell DC, Bodmer W, Tomlinson IP, Carter NP. Douglas EJ, et al. Cancer Res. 2004 Jul 15;64(14):4817-25. doi: 10.1158/0008-5472.CAN-04-0328. Cancer Res. 2004. PMID: 15256451

7

Allelic loss studies do not provide evidence for the "endometriosis-as-tumor" theory.

Prowse AH, Fakis G, Manek S, Churchman M, Edwards S, Rowan A, Koninckx P, Kennedy S, Tomlinson IP. Prowse AH, et al. Fertil Steril. 2005 Apr;83 Suppl 1:1134-43. doi: 10.1016/j.fertnstert.2004.07.982. Fertil Steril. 2005. PMID: 15831286 Free article.

8

O(6)-methylguanine methyltransferase in colorectal cancers: detection of mutations, loss of expression, and weak association with G:C>A:T transitions.

Halford S, Rowan A, Sawyer E, Talbot I, Tomlinson I. Halford S, et al. Gut. 2005 Jun;54(6):797-802. doi: 10.1136/gut.2004.059535. Gut. 2005. PMID: 15888787 Free PMC article.

9

Refining molecular analysis in the pathways of colorectal carcinogenesis.

Rowan A, Halford S, Gaasenbeek M, Kemp Z, Sieber O, Volikos E, Douglas E, Fiegler H, Carter N, Talbot I, Silver A, Tomlinson I. Rowan A, et al. Clin Gastroenterol Hepatol. 2005 Nov;3(11):1115-23. doi: 10.1016/s1542-3565(05)00618-x. Clin Gastroenterol Hepatol. 2005. PMID: 16271343

10

CDC4 mutations occur in a subset of colorectal cancers but are not predicted to cause loss of function and are not associated with chromosomal instability.

Kemp Z, Rowan A, Chambers W, Wortham N, Halford S, Sieber O, Mortensen N, von Herbay A, Gunther T, Ilyas M, Tomlinson I. Kemp Z, et al. Cancer Res. 2005 Dec 15;65(24):11361-6. doi: 10.1158/0008-5472.CAN-05-2565. Cancer Res. 2005. PMID: 16357143

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