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lncRNA DIGIT and BRD3 protein form phase-separated condensates to regulate endoderm differentiation.
Daneshvar K, Ardehali MB, Klein IA, Hsieh FK, Kratkiewicz AJ, Mahpour A, Cancelliere SOL, Zhou C, Cook BM, Li W, Pondick JV, Gupta SK, Moran SP, Young RA, Kingston RE, Mullen AC. Daneshvar K, et al. Among authors: moran sp. Nat Cell Biol. 2020 Oct;22(10):1211-1222. doi: 10.1038/s41556-020-0572-2. Epub 2020 Sep 7. Nat Cell Biol. 2020. PMID: 32895492 Free PMC article.
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in hepatic stellate cells.
Sun C, Zhou C, Daneshvar K, Kratkiewicz AJ, Saad AB, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran S, Gentile S, Rahman RU, Li Z, Sparks R, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Sun C, et al. bioRxiv [Preprint]. 2023 Jul 30:2023.07.29.551032. doi: 10.1101/2023.07.29.551032. bioRxiv. 2023. Update in: Hepatology. 2024 Apr 2. doi: 10.1097/HEP.0000000000000822 PMID: 37546982 Free PMC article. Updated. Preprint.
Conserved long noncoding RNA TILAM promotes liver fibrosis through interaction with PML in HSCs.
Sun C, Zhou C, Daneshvar K, Ben Saad A, Kratkiewicz AJ, Toles BJ, Arghiani N, Hess A, Chen JY, Pondick JV, York SR, Li W, Moran SP, Gentile SD, Rahman RU, Li Z, Zhou P, Sparks RP, Habboub T, Kim BM, Choi MY, Affo S, Schwabe RF, Popov YV, Mullen AC. Sun C, et al. Among authors: moran sp. Hepatology. 2024 Apr 2. doi: 10.1097/HEP.0000000000000822. Online ahead of print. Hepatology. 2024. PMID: 38563629
Brain-region-specific changes in neurons and glia and dysregulation of dopamine signaling in Grin2a mutant mice.
Farsi Z, Nicolella A, Simmons SK, Aryal S, Shepard N, Brenner K, Lin S, Herzog L, Moran SP, Stalnaker KJ, Shin W, Gazestani V, Song BJ, Bonanno K, Keshishian H, Carr SA, Pan JQ, Macosko EZ, Datta SR, Dejanovic B, Kim E, Levin JZ, Sheng M. Farsi Z, et al. Among authors: moran sp. Neuron. 2023 Nov 1;111(21):3378-3396.e9. doi: 10.1016/j.neuron.2023.08.004. Epub 2023 Aug 31. Neuron. 2023. PMID: 37657442 Free article.
Discovery of VU6007496: Challenges in the Development of an M1 Positive Allosteric Modulator Backup Candidate.
Engers JL, Bollinger KA, Capstick RA, Long MF, Bender AM, Dickerson JW, Peng W, Presley CC, Cho HP, Rodriguez AL, Niswender CM, Moran SP, Xiang Z, Blobaum AL, Boutaud O, Rook JM, Engers DW, Conn PJ, Lindsley CW. Engers JL, et al. Among authors: moran sp. ACS Chem Neurosci. 2024 Sep 18;15(18):3421-3433. doi: 10.1021/acschemneuro.4c00508. Epub 2024 Aug 28. ACS Chem Neurosci. 2024. PMID: 39197083 Free PMC article.
Cerebral Aβ deposition in an Aβ-precursor protein-transgenic rhesus monkey.
Chan AWS, Cho IK, Li CX, Zhang X, Patel S, Rusnak R, Raper J, Bachevalier J, Moran SP, Chi T, Cannon KH, Hunter CE, Martin RC, Xiao H, Yang SH, Gumber S, Herndon JG, Rosen RF, Hu WT, Lah JJ, Levey AI, Smith Y, Walker LC. Chan AWS, et al. Among authors: moran sp. Aging Brain. 2022;2:100044. doi: 10.1016/j.nbas.2022.100044. Epub 2022 Jun 17. Aging Brain. 2022. PMID: 36589695 Free PMC article.
Novel Fluorescence-Based High-Throughput FLIPR Assay Utilizing Membrane-Tethered Genetic Calcium Sensors to Identify T-Type Calcium Channel Modulators.
Zhang YL, Moran SP, Allen A, Baez-Nieto D, Xu Q, Wang LA, Martenis WE, Sacher JR, Gale JP, Weïwer M, Wagner FF, Pan JQ. Zhang YL, et al. Among authors: moran sp. ACS Pharmacol Transl Sci. 2022 Feb 25;5(3):156-168. doi: 10.1021/acsptsci.1c00233. eCollection 2022 Mar 11. ACS Pharmacol Transl Sci. 2022. PMID: 35311021 Free PMC article.
24 results