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Reprogrammed mRNA translation drives resistance to therapeutic targeting of ribosome biogenesis.
Kusnadi EP, Trigos AS, Cullinane C, Goode DL, Larsson O, Devlin JR, Chan KT, De Souza DP, McConville MJ, McArthur GA, Thomas G, Sanij E, Poortinga G, Hannan RD, Hannan KM, Kang J, Pearson RB. Kusnadi EP, et al. Among authors: hannan rd, hannan km. EMBO J. 2020 Nov 2;39(21):e105111. doi: 10.15252/embj.2020105111. Epub 2020 Sep 18. EMBO J. 2020. PMID: 32945574 Free PMC article.
Transcription by RNA polymerase I.
Hannan KM, Hannan RD, Rothblum LI. Hannan KM, et al. Among authors: hannan rd. Front Biosci. 1998 Mar 26;3:d376-98. doi: 10.2741/a282. Front Biosci. 1998. PMID: 9514985 Review.
mTOR-dependent regulation of ribosomal gene transcription requires S6K1 and is mediated by phosphorylation of the carboxy-terminal activation domain of the nucleolar transcription factor UBF.
Hannan KM, Brandenburger Y, Jenkins A, Sharkey K, Cavanaugh A, Rothblum L, Moss T, Poortinga G, McArthur GA, Pearson RB, Hannan RD. Hannan KM, et al. Among authors: hannan rd. Mol Cell Biol. 2003 Dec;23(23):8862-77. doi: 10.1128/MCB.23.23.8862-8877.2003. Mol Cell Biol. 2003. PMID: 14612424 Free PMC article.
MAD1 and c-MYC regulate UBF and rDNA transcription during granulocyte differentiation.
Poortinga G, Hannan KM, Snelling H, Walkley CR, Jenkins A, Sharkey K, Wall M, Brandenburger Y, Palatsides M, Pearson RB, McArthur GA, Hannan RD. Poortinga G, et al. Among authors: hannan km, hannan rd. EMBO J. 2004 Aug 18;23(16):3325-35. doi: 10.1038/sj.emboj.7600335. Epub 2004 Jul 29. EMBO J. 2004. PMID: 15282543 Free PMC article.
Chromatin organization and expression.
Sanij E, Hannan RD. Sanij E, et al. Among authors: hannan rd. Genome Biol. 2008 Apr 14;9(4):305. doi: 10.1186/gb-2008-9-4-305. Genome Biol. 2008. PMID: 18423066 Free PMC article.
140 results