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The conundrum of human immune system "senescence".
Pawelec G, Bronikowski A, Cunnane SC, Ferrucci L, Franceschi C, Fülöp T, Gaudreau P, Gladyshev VN, Gonos ES, Gorbunova V, Kennedy BK, Larbi A, Lemaître JF, Liu GH, Maier AB, Morais JA, Nóbrega OT, Moskalev A, Rikkert MO, Seluanov A, Senior AM, Ukraintseva S, Vanhaelen Q, Witkowski J, Cohen AA. Pawelec G, et al. Among authors: cunnane sc. Mech Ageing Dev. 2020 Dec;192:111357. doi: 10.1016/j.mad.2020.111357. Epub 2020 Sep 17. Mech Ageing Dev. 2020. PMID: 32949594 Free PMC article. Review.
Hyperactivation of monocytes and macrophages in MCI patients contributes to the progression of Alzheimer's disease.
Munawara U, Catanzaro M, Xu W, Tan C, Hirokawa K, Bosco N, Dumoulin D, Khalil A, Larbi A, Lévesque S, Ramassamy C, Barron AE, Cunnane S, Beauregard PB, Bellenger JP, Rodrigues S, Desroches M, Witkowski JM, Laurent B, Frost EH, Fulop T. Munawara U, et al. Immun Ageing. 2021 Jun 21;18(1):29. doi: 10.1186/s12979-021-00236-x. Immun Ageing. 2021. PMID: 34154615 Free PMC article.
Glucose hypometabolism is highly localized, but lower cortical thickness and brain atrophy are widespread in cognitively normal older adults.
Nugent S, Castellano CA, Goffaux P, Whittingstall K, Lepage M, Paquet N, Bocti C, Fulop T, Cunnane SC. Nugent S, et al. Among authors: cunnane sc. Am J Physiol Endocrinol Metab. 2014 Jun 1;306(11):E1315-21. doi: 10.1152/ajpendo.00067.2014. Epub 2014 Apr 15. Am J Physiol Endocrinol Metab. 2014. PMID: 24735889 Free article.
340 results