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Novel opioid-neurotensin-based hybrid peptide with spinal long-lasting antinociceptive activity and a propensity to delay tolerance development.
Frączek K, Ferraiolo M, Hermans E, Bujalska-Zadrozny M, Kasarello K, Erdei A, Kulik K, Kowalczyk A, Wojciechowski P, Sulejczak D, Sosnowski P, Granica S, Benyhe S, Kaczynska K, Nagraba L, Stolarczyk A, Cudnoch-Jedrzejewska A, Kleczkowska P. Frączek K, et al. Among authors: kleczkowska p. Acta Pharm Sin B. 2020 Aug;10(8):1440-1452. doi: 10.1016/j.apsb.2020.04.014. Epub 2020 May 1. Acta Pharm Sin B. 2020. PMID: 32963942 Free PMC article.
Biological evaluation and molecular docking studies of AA3052, a compound containing a μ-selective opioid peptide agonist DALDA and d-Phe-Phe-d-Phe-Leu-Leu-NH2, a substance P analogue.
Kowalczyk A, Kleczkowska P, Rękawek M, Kulik K, Lesniak A, Erdei A, Borics A, Martin C, Pawlik K, Lipkowski AW, Benyhe S, Makulska-Nowak H, Ballet S, Bujalska-Zadrozny M. Kowalczyk A, et al. Among authors: kleczkowska p. Eur J Pharm Sci. 2016 Oct 10;93:11-20. doi: 10.1016/j.ejps.2016.07.009. Epub 2016 Jul 14. Eur J Pharm Sci. 2016. PMID: 27423260
46 results