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Serine-Selective Bioconjugation.
Vantourout JC, Adusumalli SR, Knouse KW, Flood DT, Ramirez A, Padial NM, Istrate A, Maziarz K, deGruyter JN, Merchant RR, Qiao JX, Schmidt MA, Deery MJ, Eastgate MD, Dawson PE, Bernardes GJL, Baran PS. Vantourout JC, et al. Among authors: degruyter jn. J Am Chem Soc. 2020 Oct 14;142(41):17236-17242. doi: 10.1021/jacs.0c05595. Epub 2020 Oct 5. J Am Chem Soc. 2020. PMID: 32965106 Free PMC article.
Peptide Macrocyclization Inspired by Non-Ribosomal Imine Natural Products.
Malins LR, deGruyter JN, Robbins KJ, Scola PM, Eastgate MD, Ghadiri MR, Baran PS. Malins LR, et al. Among authors: degruyter jn. J Am Chem Soc. 2017 Apr 12;139(14):5233-5241. doi: 10.1021/jacs.7b01624. Epub 2017 Mar 31. J Am Chem Soc. 2017. PMID: 28326777 Free PMC article.
A General Amino Acid Synthesis Enabled by Innate Radical Cross-Coupling.
Ni S, Garrido-Castro AF, Merchant RR, de Gruyter JN, Schmitt DC, Mousseau JJ, Gallego GM, Yang S, Collins MR, Qiao JX, Yeung KS, Langley DR, Poss MA, Scola PM, Qin T, Baran PS. Ni S, et al. Angew Chem Int Ed Engl. 2018 Oct 26;57(44):14560-14565. doi: 10.1002/anie.201809310. Epub 2018 Oct 15. Angew Chem Int Ed Engl. 2018. PMID: 30212610 Free PMC article.
Unlocking P(V): Reagents for chiral phosphorothioate synthesis.
Knouse KW, deGruyter JN, Schmidt MA, Zheng B, Vantourout JC, Kingston C, Mercer SE, Mcdonald IM, Olson RE, Zhu Y, Hang C, Zhu J, Yuan C, Wang Q, Park P, Eastgate MD, Baran PS. Knouse KW, et al. Among authors: degruyter jn. Science. 2018 Sep 21;361(6408):1234-1238. doi: 10.1126/science.aau3369. Epub 2018 Aug 2. Science. 2018. PMID: 30072577 Free PMC article.
Direct Carbon Isotope Exchange through Decarboxylative Carboxylation.
Kingston C, Wallace MA, Allentoff AJ, deGruyter JN, Chen JS, Gong SX, Bonacorsi S Jr, Baran PS. Kingston C, et al. Among authors: degruyter jn. J Am Chem Soc. 2019 Jan 16;141(2):774-779. doi: 10.1021/jacs.8b12035. Epub 2019 Jan 3. J Am Chem Soc. 2019. PMID: 30605319 Free PMC article.
Electrochemically Driven, Ni-Catalyzed Aryl Amination: Scope, Mechanism, and Applications.
Kawamata Y, Vantourout JC, Hickey DP, Bai P, Chen L, Hou Q, Qiao W, Barman K, Edwards MA, Garrido-Castro AF, deGruyter JN, Nakamura H, Knouse K, Qin C, Clay KJ, Bao D, Li C, Starr JT, Garcia-Irizarry C, Sach N, White HS, Neurock M, Minteer SD, Baran PS. Kawamata Y, et al. Among authors: degruyter jn. J Am Chem Soc. 2019 Apr 17;141(15):6392-6402. doi: 10.1021/jacs.9b01886. Epub 2019 Apr 2. J Am Chem Soc. 2019. PMID: 30905151 Free PMC article.
Residue-Specific Peptide Modification: A Chemist's Guide.
deGruyter JN, Malins LR, Baran PS. deGruyter JN, et al. Biochemistry. 2017 Aug 1;56(30):3863-3873. doi: 10.1021/acs.biochem.7b00536. Epub 2017 Jul 17. Biochemistry. 2017. PMID: 28653834 Free PMC article. Review.
Alkyl Sulfinates: Radical Precursors Enabling Drug Discovery.
Smith JM, Dixon JA, deGruyter JN, Baran PS. Smith JM, et al. Among authors: degruyter jn. J Med Chem. 2019 Mar 14;62(5):2256-2264. doi: 10.1021/acs.jmedchem.8b01303. Epub 2018 Oct 16. J Med Chem. 2019. PMID: 30272973 Review.
CITU: A Peptide and Decarboxylative Coupling Reagent.
deGruyter JN, Malins LR, Wimmer L, Clay KJ, Lopez-Ogalla J, Qin T, Cornella J, Liu Z, Che G, Bao D, Stevens JM, Qiao JX, Allen MP, Poss MA, Baran PS. deGruyter JN, et al. Org Lett. 2017 Nov 17;19(22):6196-6199. doi: 10.1021/acs.orglett.7b03121. Epub 2017 Nov 8. Org Lett. 2017. PMID: 29115835 Free PMC article.
13 results