Xu L - Search Results

1

Cockayne syndrome B protein acts as an ATP-dependent processivity factor that helps RNA polymerase II overcome nucleosome barriers.

Xu J, Wang W, Xu L, Chen JY, Chong J, Oh J, Leschziner AE, Fu XD, Wang D. Xu J, et al. Among authors: xu l. Proc Natl Acad Sci U S A. 2020 Oct 13;117(41):25486-25493. doi: 10.1073/pnas.2013379117. Epub 2020 Sep 28. Proc Natl Acad Sci U S A. 2020. PMID: 32989164 Free PMC article.

2

RNA polymerase II acts as a selective sensor for DNA lesions and endogenous DNA modifications.

Shin JH, Xu L, Wang D. Shin JH, et al. Among authors: xu l. Transcription. 2016 May 26;7(3):57-62. doi: 10.1080/21541264.2016.1168506. Epub 2016 Apr 22. Transcription. 2016. PMID: 27105138 Free PMC article.

3

RNA polymerase II senses obstruction in the DNA minor groove via a conserved sensor motif.

Xu L, Wang W, Gotte D, Yang F, Hare AA, Welch TR, Li BC, Shin JH, Chong J, Strathern JN, Dervan PB, Wang D. Xu L, et al. Proc Natl Acad Sci U S A. 2016 Nov 1;113(44):12426-12431. doi: 10.1073/pnas.1612745113. Epub 2016 Oct 17. Proc Natl Acad Sci U S A. 2016. PMID: 27791148 Free PMC article.

4

Mechanism of DNA alkylation-induced transcriptional stalling, lesion bypass, and mutagenesis.

Xu L, Wang W, Wu J, Shin JH, Wang P, Unarta IC, Chong J, Wang Y, Wang D. Xu L, et al. Proc Natl Acad Sci U S A. 2017 Aug 22;114(34):E7082-E7091. doi: 10.1073/pnas.1708748114. Epub 2017 Aug 7. Proc Natl Acad Sci U S A. 2017. PMID: 28784758 Free PMC article.

5

Strand-specific (asymmetric) contribution of phosphodiester linkages on RNA polymerase II transcriptional efficiency and fidelity.

Xu L, Zhang L, Chong J, Xu J, Huang X, Wang D. Xu L, et al. Among authors: xu j. Proc Natl Acad Sci U S A. 2014 Aug 12;111(32):E3269-76. doi: 10.1073/pnas.1406234111. Epub 2014 Jul 29. Proc Natl Acad Sci U S A. 2014. PMID: 25074911 Free PMC article.

6

Impact of template backbone heterogeneity on RNA polymerase II transcription.

Xu L, Wang W, Zhang L, Chong J, Huang X, Wang D. Xu L, et al. Nucleic Acids Res. 2015 Feb 27;43(4):2232-41. doi: 10.1093/nar/gkv059. Epub 2015 Feb 6. Nucleic Acids Res. 2015. PMID: 25662224 Free PMC article.

7

RNA polymerase II transcriptional fidelity control and its functional interplay with DNA modifications.

Xu L, Wang W, Chong J, Shin JH, Xu J, Wang D. Xu L, et al. Among authors: xu j. Crit Rev Biochem Mol Biol. 2015;50(6):503-19. doi: 10.3109/10409238.2015.1087960. Epub 2015 Sep 22. Crit Rev Biochem Mol Biol. 2015. PMID: 26392149 Free PMC article. Review.

8

Transcriptional processing of an unnatural base pair by eukaryotic RNA polymerase II.

Oh J, Shin J, Unarta IC, Wang W, Feldman AW, Karadeema RJ, Xu L, Xu J, Chong J, Krishnamurthy R, Huang X, Romesberg FE, Wang D. Oh J, et al. Among authors: xu l, xu j. Nat Chem Biol. 2021 Aug;17(8):906-914. doi: 10.1038/s41589-021-00817-3. Epub 2021 Jun 17. Nat Chem Biol. 2021. PMID: 34140682 Free PMC article.

9

Dissecting the chemical interactions and substrate structural signatures governing RNA polymerase II trigger loop closure by synthetic nucleic acid analogues.

Xu L, Butler KV, Chong J, Wengel J, Kool ET, Wang D. Xu L, et al. Nucleic Acids Res. 2014 May;42(9):5863-70. doi: 10.1093/nar/gku238. Epub 2014 Apr 1. Nucleic Acids Res. 2014. PMID: 24692664 Free PMC article.

10

Molecular basis for 5-carboxycytosine recognition by RNA polymerase II elongation complex.

Wang L, Zhou Y, Xu L, Xiao R, Lu X, Chen L, Chong J, Li H, He C, Fu XD, Wang D. Wang L, et al. Among authors: xu l. Nature. 2015 Jul 30;523(7562):621-5. doi: 10.1038/nature14482. Epub 2015 Jun 29. Nature. 2015. PMID: 26123024 Free PMC article.

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