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Acute SARS-CoV-2 Infection is Highly Cytopathic, Elicits a Robust Innate Immune Response and is Efficiently Prevented by EIDD-2801.
Wahl A, Gralinski L, Johnson C, Yao W, Kovarova M, Dinnon K, Liu H, Madden V, Krzystek H, De C, White K, Schäfer A, Zaman T, Leist S, Grant P, Gully K, Askin F, Browne E, Jones C, Pickles R, Baric R, Garcia JV. Wahl A, et al. Among authors: kovarova m. Res Sq [Preprint]. 2020 Sep 24:rs.3.rs-80404. doi: 10.21203/rs.3.rs-80404/v1. Res Sq. 2020. Update in: Nature. 2021 Mar;591(7850):451-457. doi: 10.1038/s41586-021-03312-w PMID: 32995766 Free PMC article. Updated. Preprint.
SARS-CoV-2 infection is effectively treated and prevented by EIDD-2801.
Wahl A, Gralinski LE, Johnson CE, Yao W, Kovarova M, Dinnon KH 3rd, Liu H, Madden VJ, Krzystek HM, De C, White KK, Gully K, Schäfer A, Zaman T, Leist SR, Grant PO, Bluemling GR, Kolykhalov AA, Natchus MG, Askin FB, Painter G, Browne EP, Jones CD, Pickles RJ, Baric RS, Garcia JV. Wahl A, et al. Among authors: kovarova m. Nature. 2021 Mar;591(7850):451-457. doi: 10.1038/s41586-021-03312-w. Epub 2021 Feb 9. Nature. 2021. PMID: 33561864 Free PMC article.
Analysis of the effect of HDAC inhibitors on the formation of the HIV reservoir.
Ling L, Kim M, Soper A, Kovarova M, Spagnuolo RA, Begum N, Kirchherr J, Archin N, Battaglia D, Cleveland D, Wahl A, Margolis DM, Browne EP, Garcia JV. Ling L, et al. Among authors: kovarova m. mBio. 2024 Sep 11;15(9):e0163224. doi: 10.1128/mbio.01632-24. Epub 2024 Aug 13. mBio. 2024. PMID: 39136440 Free PMC article.
Robust and persistent reactivation of SIV and HIV by N-803 and depletion of CD8+ cells.
McBrien JB, Mavigner M, Franchitti L, Smith SA, White E, Tharp GK, Walum H, Busman-Sahay K, Aguilera-Sandoval CR, Thayer WO, Spagnuolo RA, Kovarova M, Wahl A, Cervasi B, Margolis DM, Vanderford TH, Carnathan DG, Paiardini M, Lifson JD, Lee JH, Safrit JT, Bosinger SE, Estes JD, Derdeyn CA, Garcia JV, Kulpa DA, Chahroudi A, Silvestri G. McBrien JB, et al. Among authors: kovarova m. Nature. 2020 Feb;578(7793):154-159. doi: 10.1038/s41586-020-1946-0. Epub 2020 Jan 22. Nature. 2020. PMID: 31969705 Free PMC article.
117 results