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Fatty acid oxidation of alternatively activated macrophages prevents foam cell formation, but Mycobacterium tuberculosis counteracts this process via HIF-1α activation.
Genoula M, Marín Franco JL, Maio M, Dolotowicz B, Ferreyra M, Milillo MA, Mascarau R, Moraña EJ, Palmero D, Matteo M, Fuentes F, López B, Barrionuevo P, Neyrolles O, Cougoule C, Lugo-Villarino G, Vérollet C, Sasiain MDC, Balboa L. Genoula M, et al. Among authors: milillo ma. PLoS Pathog. 2020 Oct 1;16(10):e1008929. doi: 10.1371/journal.ppat.1008929. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33002063 Free PMC article.
B. abortus RNA is the component involved in the down-modulation of MHC-I expression on human monocytes via TLR8 and the EGFR pathway.
Milillo MA, Velásquez LN, Trotta A, Delpino MV, Marinho FV, Balboa L, Vermeulen M, Espindola SL, Rodriguez-Rodrigues N, Fernández GC, Oliveira SC, Giambartolomei GH, Barrionuevo P. Milillo MA, et al. PLoS Pathog. 2017 Aug 2;13(8):e1006527. doi: 10.1371/journal.ppat.1006527. eCollection 2017 Aug. PLoS Pathog. 2017. PMID: 28767704 Free PMC article.
Brucella abortus-infected platelets modulate the activation of neutrophils.
Trotta A, Milillo MA, Serafino A, Castillo LA, Birnberg Weiss F, Delpino MV, Giambartolomei GH, Fernández GC, Barrionuevo P. Trotta A, et al. Among authors: milillo ma. Immunol Cell Biol. 2020 Oct;98(9):743-756. doi: 10.1111/imcb.12373. Epub 2020 Aug 4. Immunol Cell Biol. 2020. PMID: 32623755
Brucella abortus RNA does not polarize macrophages to a particular profile but interferes with M1 polarization.
Serafino A, Marin Franco JL, Maio M, Trotta A, Genoula M, Castillo LA, Birnberg Weiss F, Pittaluga JR, Balboa L, Barrionuevo P, Milillo MA. Serafino A, et al. Among authors: milillo ma. PLoS Negl Trop Dis. 2022 Nov 28;16(11):e0010950. doi: 10.1371/journal.pntd.0010950. eCollection 2022 Nov. PLoS Negl Trop Dis. 2022. PMID: 36441810 Free PMC article.
22 results