Hummel AM - Search Results

1

Clinical Utility of Serial Measurements of Antineutrophil Cytoplasmic Antibodies Targeting Proteinase 3 in ANCA-Associated Vasculitis.

Thompson GE, Fussner LA, Hummel AM, Schroeder DR, Silva F, Snyder MR, Langford CA, Merkel PA, Monach PA, Seo P, Spiera RF, St Clair EW, Stone JH, Specks U. Thompson GE, et al. Among authors: hummel am. Front Immunol. 2020 Sep 3;11:2053. doi: 10.3389/fimmu.2020.02053. eCollection 2020. Front Immunol. 2020. PMID: 33013868 Free PMC article. Clinical Trial.

2

Recombinant human proteinase 3, the Wegener's autoantigen, expressed in HMC-1 cells is enzymatically active and recognized by c-ANCA.

Specks U, Fass DN, Fautsch MP, Hummel AM, Viss MA. Specks U, et al. Among authors: hummel am. FEBS Lett. 1996 Jul 29;390(3):265-70. doi: 10.1016/0014-5793(96)00669-2. FEBS Lett. 1996. PMID: 8706874 Free article.

3

Cloning and functional expression of the murine homologue of proteinase 3: implications for the design of murine models of vasculitis.

Jenne DE, Fröhlich L, Hummel AM, Specks U. Jenne DE, et al. Among authors: hummel am. FEBS Lett. 1997 May 19;408(2):187-90. doi: 10.1016/s0014-5793(97)00418-3. FEBS Lett. 1997. PMID: 9187364 Free article.

4

A proportion of proteinase 3 (PR3)-specific anti-neutrophil cytoplasmic antibodies (ANCA) only react with PR3 after cleavage of its N-terminal activation dipeptide.

Sun J, Fass DN, Viss MA, Hummel AM, Tang H, Homburger HA, Specks U. Sun J, et al. Among authors: hummel am. Clin Exp Immunol. 1998 Nov;114(2):320-6. doi: 10.1046/j.1365-2249.1998.00730.x. Clin Exp Immunol. 1998. PMID: 9822293 Free PMC article.

5

Effects of carboxy-terminal modifications of proteinase 3 (PR3) on the recognition by PR3-ANCA.

Capizzi SA, Viss MA, Hummel AM, Fass DN, Specks U. Capizzi SA, et al. Among authors: hummel am. Kidney Int. 2003 Feb;63(2):756-60. doi: 10.1046/j.1523-1755.2003.00765.x. Kidney Int. 2003. PMID: 12631144 Free article.

6

Differences between human proteinase 3 and neutrophil elastase and their murine homologues are relevant for murine model experiments.

Wiesner O, Litwiller RD, Hummel AM, Viss MA, McDonald CJ, Jenne DE, Fass DN, Specks U. Wiesner O, et al. Among authors: hummel am. FEBS Lett. 2005 Oct 10;579(24):5305-12. doi: 10.1016/j.febslet.2005.08.056. FEBS Lett. 2005. PMID: 16182289 Free article.

7

A novel capture-ELISA for detection of anti-neutrophil cytoplasmic antibodies (ANCA) based on c-myc peptide recognition in carboxy-terminally tagged recombinant neutrophil serine proteases.

Lee AS, Finkielman JD, Peikert T, Hummel AM, Viss MA, Specks U. Lee AS, et al. Among authors: hummel am. J Immunol Methods. 2005 Dec 20;307(1-2):62-72. doi: 10.1016/j.jim.2005.09.004. Epub 2005 Oct 3. J Immunol Methods. 2005. PMID: 16242707

8

Agreement of anti-neutrophil cytoplasmic antibody measurements obtained from serum and plasma.

Lee AS, Finkielman JD, Peikert T, Hummel AM, Viss MA, Jacob GL, Homburger HA, Specks U; Wegener's Granulomatosis Etanercept Trial Research Group. Lee AS, et al. Among authors: hummel am. Clin Exp Immunol. 2006 Oct;146(1):15-20. doi: 10.1111/j.1365-2249.2006.03179.x. Clin Exp Immunol. 2006. PMID: 16968393 Free PMC article.

9

Functional significance of Asn-linked glycosylation of proteinase 3 for enzymatic activity, processing, targeting, and recognition by anti-neutrophil cytoplasmic antibodies.

Specks U, Fass DN, Finkielman JD, Hummel AM, Viss MA, Litwiller RD, McDonald CJ. Specks U, et al. Among authors: hummel am. J Biochem. 2007 Jan;141(1):101-12. doi: 10.1093/jb/mvm008. Epub 2006 Dec 11. J Biochem. 2007. PMID: 17158864

10

ANCA are detectable in nearly all patients with active severe Wegener's granulomatosis.

Finkielman JD, Lee AS, Hummel AM, Viss MA, Jacob GL, Homburger HA, Peikert T, Hoffman GS, Merkel PA, Spiera R, St Clair EW, Davis JC Jr, McCune WJ, Tibbs AK, Ytterberg SR, Stone JH, Specks U; WGET Research Group. Finkielman JD, et al. Among authors: hummel am. Am J Med. 2007 Jul;120(7):643.e9-14. doi: 10.1016/j.amjmed.2006.08.016. Am J Med. 2007. PMID: 17602941

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