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Plasma DNA Profile Associated with DNASE1L3 Gene Mutations: Clinical Observations, Relationships to Nuclease Substrate Preference, and In Vivo Correction.
Chan RWY, Serpas L, Ni M, Volpi S, Hiraki LT, Tam LS, Rashidfarrokhi A, Wong PCH, Tam LHP, Wang Y, Jiang P, Cheng ASH, Peng W, Han DSC, Tse PPP, Lau PK, Lee WS, Magnasco A, Buti E, Sisirak V, AlMutairi N, Chan KCA, Chiu RWK, Reizis B, Lo YMD. Chan RWY, et al. Among authors: ni m. Am J Hum Genet. 2020 Nov 5;107(5):882-894. doi: 10.1016/j.ajhg.2020.09.006. Epub 2020 Oct 5. Am J Hum Genet. 2020. PMID: 33022220 Free PMC article.
Fragmentomics of urinary cell-free DNA in nuclease knockout mouse models.
Chen M, Chan RWY, Cheung PPH, Ni M, Wong DKL, Zhou Z, Ma ML, Huang L, Xu X, Lee WS, Wang G, Lui KO, Lam WKJ, Teoh JYC, Ng CF, Jiang P, Chan KCA, Chiu RWK, Lo YMD. Chen M, et al. Among authors: ni m. PLoS Genet. 2022 Jul 6;18(7):e1010262. doi: 10.1371/journal.pgen.1010262. eCollection 2022 Jul. PLoS Genet. 2022. PMID: 35793278 Free PMC article.
Nuclease deficiencies alter plasma cell-free DNA methylation profiles.
Han DSC, Ni M, Chan RWY, Wong DKL, Hiraki LT, Volpi S, Jiang P, Lui KO, Chan KCA, Chiu RWK, Lo YMD. Han DSC, et al. Among authors: ni m. Genome Res. 2021 Nov;31(11):2008-2021. doi: 10.1101/gr.275426.121. Epub 2021 Sep 1. Genome Res. 2021. PMID: 34470801 Free PMC article.
Dnase1l3 deletion causes aberrations in length and end-motif frequencies in plasma DNA.
Serpas L, Chan RWY, Jiang P, Ni M, Sun K, Rashidfarrokhi A, Soni C, Sisirak V, Lee WS, Cheng SH, Peng W, Chan KCA, Chiu RWK, Reizis B, Lo YMD. Serpas L, et al. Among authors: ni m. Proc Natl Acad Sci U S A. 2019 Jan 8;116(2):641-649. doi: 10.1073/pnas.1815031116. Epub 2018 Dec 28. Proc Natl Acad Sci U S A. 2019. PMID: 30593563 Free PMC article.
1,743 results