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A concise route to MK-4482 (EIDD-2801) from cytidine.
Vasudevan N , Ahlqvist GP , McGeough CP , Paymode DJ , Cardoso FSP , Lucas T , Dietz JP , Opatz T , Jamison TF , Gupton FB , Snead DR . Vasudevan N , et al. Among authors: opatz t. Chem Commun (Camb). 2020 Nov 11;56(87):13363-13364. doi: 10.1039/d0cc05944g. Epub 2020 Oct 8. Chem Commun (Camb). 2020. PMID: 33030468
Di-tert-butyl Phosphonate Route to the Antiviral Drug Tenofovir.
Dietz JP, Ferenc D, Jamison TF, Gupton BF, Opatz T. Dietz JP, et al. Among authors: opatz t. Org Process Res Dev. 2021 Feb 11;25(4):789-798. doi: 10.1021/acs.oprd.0c00473. eCollection 2021 Apr 16. Org Process Res Dev. 2021. PMID: 37556249 Review.
Total synthesis and biological evaluation of seven new anti-inflammatory oxacyclododecindione-type macrolactones.
Weber C, Vierengel N, Walter T, Behrendt T, Lucas T, Erkel G, Opatz T. Weber C, et al. Among authors: opatz t. Org Biomol Chem. 2020 Aug 5;18(30):5906-5917. doi: 10.1039/d0ob00958j. Org Biomol Chem. 2020. PMID: 32691816
Through variation of our previously published total synthesis of two highly active anti-inflammatory macrolactones from the oxacyclododecindione family (J. Tauber, M. Rohr, T. Walter, G. Erkel and T. Opatz, Org. Biomol. Chem., 2015, 13, 7813-7821), seven new …
Through variation of our previously published total synthesis of two highly active anti-inflammatory macrolactones from the oxacyclododecind …
Structure elucidation of the novel synthetic cannabinoid Cumyl-Tosyl-Indazole-3-Carboxamide (Cumyl-TsINACA) found in illicit products in Germany.
Pulver B, Schönberger T, Weigel D, Köck M, Eschenlohr Y, Lucas T, Podlesnik N, Opatz T, Dreiseitel W, Pütz M, Schäper J, Jacobsen-Bauer A, Auwärter V, Westphal F. Pulver B, et al. Among authors: opatz t. Drug Test Anal. 2022 Aug;14(8):1387-1406. doi: 10.1002/dta.3261. Epub 2022 Apr 9. Drug Test Anal. 2022. PMID: 35338591
216 results