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CDKN2A/p16INK4a suppresses hepatic fatty acid oxidation through the AMPKα2-SIRT1-PPARα signaling pathway.
Deleye Y, Cotte AK, Hannou SA, Hennuyer N, Bernard L, Derudas B, Caron S, Legry V, Vallez E, Dorchies E, Martin N, Lancel S, Annicotte JS, Bantubungi K, Pourtier A, Raverdy V, Pattou F, Lefebvre P, Abbadie C, Staels B, Haas JT, Paumelle R. Deleye Y, et al. Among authors: derudas b. J Biol Chem. 2020 Dec 11;295(50):17310-17322. doi: 10.1074/jbc.RA120.012543. Epub 2020 Oct 9. J Biol Chem. 2020. PMID: 33037071 Free PMC article.
Regulation of bile acid synthesis by the nuclear receptor Rev-erbalpha.
Duez H, van der Veen JN, Duhem C, Pourcet B, Touvier T, Fontaine C, Derudas B, Baugé E, Havinga R, Bloks VW, Wolters H, van der Sluijs FH, Vennström B, Kuipers F, Staels B. Duez H, et al. Among authors: derudas b. Gastroenterology. 2008 Aug;135(2):689-98. doi: 10.1053/j.gastro.2008.05.035. Epub 2008 May 15. Gastroenterology. 2008. PMID: 18565334
Peroxisome-proliferator-activated receptor-alpha activation protects brain capillary endothelial cells from oxygen-glucose deprivation-induced hyperpermeability in the blood-brain barrier.
Mysiorek C, Culot M, Dehouck L, Derudas B, Staels B, Bordet R, Cecchelli R, Fenart L, Berezowski V. Mysiorek C, et al. Among authors: derudas b. Curr Neurovasc Res. 2009 Aug;6(3):181-93. doi: 10.2174/156720209788970081. Epub 2009 Aug 1. Curr Neurovasc Res. 2009. PMID: 19534718
Human atherosclerotic plaque alternative macrophages display low cholesterol handling but high phagocytosis because of distinct activities of the PPARγ and LXRα pathways.
Chinetti-Gbaguidi G, Baron M, Bouhlel MA, Vanhoutte J, Copin C, Sebti Y, Derudas B, Mayi T, Bories G, Tailleux A, Haulon S, Zawadzki C, Jude B, Staels B. Chinetti-Gbaguidi G, et al. Among authors: derudas b. Circ Res. 2011 Apr 15;108(8):985-95. doi: 10.1161/CIRCRESAHA.110.233775. Epub 2011 Feb 24. Circ Res. 2011. PMID: 21350215 Free PMC article.
Downregulation of the tumour suppressor p16INK4A contributes to the polarisation of human macrophages toward an adipose tissue macrophage (ATM)-like phenotype.
Fuentes L, Wouters K, Hannou SA, Cudejko C, Rigamonti E, Mayi TH, Derudas B, Pattou F, Chinetti-Gbaguidi G, Staels B, Paumelle R. Fuentes L, et al. Among authors: derudas b. Diabetologia. 2011 Dec;54(12):3150-6. doi: 10.1007/s00125-011-2324-0. Epub 2011 Oct 4. Diabetologia. 2011. PMID: 21968977 Free PMC article.
46 results