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The new small tyrosine kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs.
Soncini D, Orecchioni S, Ruberti S, Minetto P, Martinuzzi C, Agnelli L, Todoerti K, Cagnetta A, Miglino M, Clavio M, Contini P, Varaldo R, Bergamaschi M, Guolo F, Passalacqua M, Nencioni A, Monacelli F, Gobbi M, Neri A, Abbadessa G, Eathiraj S, Schwartz B, Bertolini F, Lemoli RM, Cea M. Soncini D, et al. Among authors: bertolini f. Haematologica. 2020 Oct 1;105(10):2420-2431. doi: 10.3324/haematol.2019.224956. Haematologica. 2020. PMID: 33054082 Free PMC article.
Stem cell plasticity: time for a reappraisal?
Lemoli RM, Bertolini F, Cancedda R, De Luca M, Del Santo A, Ferrari G, Ferrari S, Martino G, Mavilio F, Tura S. Lemoli RM, et al. Among authors: bertolini f. Haematologica. 2005 Mar;90(3):360-81. Haematologica. 2005. PMID: 15749669 Free article. Review.
Complementary populations of human adipose CD34+ progenitor cells promote growth, angiogenesis, and metastasis of breast cancer.
Orecchioni S, Gregato G, Martin-Padura I, Reggiani F, Braidotti P, Mancuso P, Calleri A, Quarna J, Marighetti P, Aldeni C, Pruneri G, Martella S, Manconi A, Petit JY, Rietjens M, Bertolini F. Orecchioni S, et al. Among authors: bertolini f. Cancer Res. 2013 Oct 1;73(19):5880-91. doi: 10.1158/0008-5472.CAN-13-0821. Epub 2013 Aug 5. Cancer Res. 2013. PMID: 23918796
Paradoxic effects of metformin on endothelial cells and angiogenesis.
Dallaglio K, Bruno A, Cantelmo AR, Esposito AI, Ruggiero L, Orecchioni S, Calleri A, Bertolini F, Pfeffer U, Noonan DM, Albini A. Dallaglio K, et al. Among authors: bertolini f. Carcinogenesis. 2014 May;35(5):1055-66. doi: 10.1093/carcin/bgu001. Epub 2014 Jan 13. Carcinogenesis. 2014. PMID: 24419232 Free PMC article.
The biguanides metformin and phenformin inhibit angiogenesis, local and metastatic growth of breast cancer by targeting both neoplastic and microenvironment cells.
Orecchioni S, Reggiani F, Talarico G, Mancuso P, Calleri A, Gregato G, Labanca V, Noonan DM, Dallaglio K, Albini A, Bertolini F. Orecchioni S, et al. Among authors: bertolini f. Int J Cancer. 2015 Mar 15;136(6):E534-44. doi: 10.1002/ijc.29193. Epub 2014 Sep 18. Int J Cancer. 2015. PMID: 25196138
547 results