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The new small tyrosine kinase inhibitor ARQ531 targets acute myeloid leukemia cells by disrupting multiple tumor-addicted programs.
Soncini D, Orecchioni S, Ruberti S, Minetto P, Martinuzzi C, Agnelli L, Todoerti K, Cagnetta A, Miglino M, Clavio M, Contini P, Varaldo R, Bergamaschi M, Guolo F, Passalacqua M, Nencioni A, Monacelli F, Gobbi M, Neri A, Abbadessa G, Eathiraj S, Schwartz B, Bertolini F, Lemoli RM, Cea M. Soncini D, et al. Among authors: orecchioni s. Haematologica. 2020 Oct 1;105(10):2420-2431. doi: 10.3324/haematol.2019.224956. Haematologica. 2020. PMID: 33054082 Free PMC article.
Paradoxic effects of metformin on endothelial cells and angiogenesis.
Dallaglio K, Bruno A, Cantelmo AR, Esposito AI, Ruggiero L, Orecchioni S, Calleri A, Bertolini F, Pfeffer U, Noonan DM, Albini A. Dallaglio K, et al. Among authors: orecchioni s. Carcinogenesis. 2014 May;35(5):1055-66. doi: 10.1093/carcin/bgu001. Epub 2014 Jan 13. Carcinogenesis. 2014. PMID: 24419232 Free PMC article.
Characterization of Cancer Stem Cells.
Orecchioni S, Bertolini F. Orecchioni S, et al. Methods Mol Biol. 2016;1464:49-62. doi: 10.1007/978-1-4939-3999-2_5. Methods Mol Biol. 2016. PMID: 27858355 Review.
Extracellular ATP induces apoptosis through P2X7R activation in acute myeloid leukemia cells but not in normal hematopoietic stem cells.
Salvestrini V, Orecchioni S, Talarico G, Reggiani F, Mazzetti C, Bertolini F, Orioli E, Adinolfi E, Di Virgilio F, Pezzi A, Cavo M, Lemoli RM, Curti A. Salvestrini V, et al. Among authors: orecchioni s. Oncotarget. 2017 Jan 24;8(4):5895-5908. doi: 10.18632/oncotarget.13927. Oncotarget. 2017. PMID: 27980223 Free PMC article.
44 results