Sinha SC - Search Results

1

Brain Permeable Tafamidis Amide Analogs for Stabilizing TTR and Reducing APP Cleavage.

Sinha A, Chang JC, Xu P, Gindinova K, Cho Y, Sun W, Wu X, Li YM, Greengard P, Kelly JW, Sinha SC. Sinha A, et al. Among authors: sinha sc. ACS Med Chem Lett. 2020 Mar 12;11(10):1973-1979. doi: 10.1021/acsmedchemlett.9b00688. eCollection 2020 Oct 8. ACS Med Chem Lett. 2020. PMID: 33062181 Free PMC article.

2

Total synthesis of asimicin and bullatacin.

Avedissian H, Sinha SC, Yazbak A, Sinha A, Neogi P, Sinha SC, Keinan E. Avedissian H, et al. Among authors: sinha a, sinha sc. J Org Chem. 2000 Sep 22;65(19):6035-51. doi: 10.1021/jo000500a. J Org Chem. 2000. PMID: 10987938

3

Toward Chemical Libraries of Annonaceous Acetogenins. Total Synthesis of Trilobacin.

Sinha SC, Sinha A, Yazbak A, Keinan E. Sinha SC, et al. Among authors: sinha a. J Org Chem. 1996 Nov 1;61(22):7640-7641. doi: 10.1021/jo961286m. J Org Chem. 1996. PMID: 11667706 No abstract available.

4

Gleevec shifts APP processing from a β-cleavage to a nonamyloidogenic cleavage.

Netzer WJ, Bettayeb K, Sinha SC, Flajolet M, Greengard P, Bustos V. Netzer WJ, et al. Among authors: sinha sc. Proc Natl Acad Sci U S A. 2017 Feb 7;114(6):1389-1394. doi: 10.1073/pnas.1620963114. Epub 2017 Jan 23. Proc Natl Acad Sci U S A. 2017. PMID: 28115709 Free PMC article.

5

Bidirectional regulation of Aβ levels by Presenilin 1.

Bustos V, Pulina MV, Kelahmetoglu Y, Sinha SC, Gorelick FS, Flajolet M, Greengard P. Bustos V, et al. Among authors: sinha sc. Proc Natl Acad Sci U S A. 2017 Jul 3;114(27):7142-7147. doi: 10.1073/pnas.1705235114. Epub 2017 May 22. Proc Natl Acad Sci U S A. 2017. PMID: 28533411 Free PMC article.

6

Development of Gleevec Analogues for Reducing Production of β-Amyloid Peptides through Shifting β-Cleavage of Amyloid Precursor Proteins.

Sun W, Netzer WJ, Sinha A, Gindinova K, Chang E, Sinha SC. Sun W, et al. Among authors: sinha a, sinha sc. J Med Chem. 2019 Mar 28;62(6):3122-3134. doi: 10.1021/acs.jmedchem.8b02007. Epub 2019 Mar 15. J Med Chem. 2019. PMID: 30873837

7

Development of Kinase Inactive PD173955 Analogues for Reducing Production of Aβ Peptides.

Sinha A, Gindinova K, Mui E, Netzer WJ, Sinha SC. Sinha A, et al. Among authors: sinha sc. ACS Med Chem Lett. 2019 Sep 6;10(10):1430-1435. doi: 10.1021/acsmedchemlett.9b00213. eCollection 2019 Oct 10. ACS Med Chem Lett. 2019. PMID: 31620229 Free PMC article.

8

Reduced Kv3.1 Activity in Dentate Gyrus Parvalbumin Cells Induces Vulnerability to Depression.

Medrihan L, Umschweif G, Sinha A, Reed S, Lee J, Gindinova K, Sinha SC, Greengard P, Sagi Y. Medrihan L, et al. Among authors: sinha a, sinha sc. Biol Psychiatry. 2020 Sep 1;88(5):405-414. doi: 10.1016/j.biopsych.2020.02.1179. Epub 2020 Mar 4. Biol Psychiatry. 2020. PMID: 32331822 Free article.

9

A Pentacyclic Triterpene from Ligustrum lucidum Targets γ-Secretase.

Luo W, Ip FCF, Fu G, Cheung K, Tian Y, Hu Y, Sinha A, Cheng EYL, Wu X, Bustos V, Greengard P, Li YM, Sinha SC, Ip NY. Luo W, et al. Among authors: sinha a, sinha sc. ACS Chem Neurosci. 2020 Sep 16;11(18):2827-2835. doi: 10.1021/acschemneuro.0c00389. Epub 2020 Sep 3. ACS Chem Neurosci. 2020. PMID: 32786303 Free PMC article.

10

Rational Development of a Small-Molecule Activator of CK1γ2 That Decreases C99 and Beta-Amyloid Levels.

Bustos VH, Sunkari YK, Sinha A, Pulina M, Bispo A, Hopkins M, Lam A, Kriegsman SF, Mui E, Chang E, Jedlicki A, Rosenthal H, Flajolet M, Sinha SC. Bustos VH, et al. Among authors: sinha sc. ACS Chem Biol. 2024 Jan 19;19(1):37-47. doi: 10.1021/acschembio.3c00425. Epub 2023 Dec 11. ACS Chem Biol. 2024. PMID: 38079390

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