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A Novel BRD Family PROTAC Inhibitor dBET1 Exerts Great Anti-Cancer Effects by Targeting c-MYC in Acute Myeloid Leukemia Cells.
Zhang K, Gao L, Wang J, Chu X, Zhang Z, Zhang Y, Fang F, Tao Y, Li X, Tian Y, Li Z, Sang X, Ma L, Lu L, Chen Y, Yu J, Zhuo R, Wu S, Pan J, Hu S. Zhang K, et al. Among authors: zhang z, zhang y. Pathol Oncol Res. 2022 Jun 27;28:1610447. doi: 10.3389/pore.2022.1610447. eCollection 2022. Pathol Oncol Res. 2022. PMID: 35832114 Free PMC article.
Super-enhancer profiling identifies novel critical and targetable cancer survival gene LYL1 in pediatric acute myeloid leukemia.
Fang F, Lu J, Sang X, Tao YF, Wang JW, Zhang ZM, Zhang YP, Li XL, Xie Y, Wu SY, Chu XR, Li G, Wu D, Chen YL, Yu JJ, Jia SQ, Feng CX, Tian YY, Li ZH, Ling J, Hu SY, Pan J. Fang F, et al. Among authors: zhang yp, zhang zm. J Exp Clin Cancer Res. 2022 Jul 16;41(1):225. doi: 10.1186/s13046-022-02428-9. J Exp Clin Cancer Res. 2022. PMID: 35842703 Free PMC article.
BRD4 Inhibitor GNE-987 Exerts Anticancer Effects by Targeting Super-Enhancer-Related Gene LYL1 in Acute Myeloid Leukemia.
Sang X, Zhang Y, Fang F, Gao L, Tao Y, Li X, Zhang Z, Wang J, Tian Y, Li Z, Yao D, Wu Y, Chu X, Zhang K, Ma L, Lu L, Chen Y, Yu J, Zhuo R, Wu S, Zhang Z, Pan J, Hu S. Sang X, et al. Among authors: zhang z, zhang k, zhang y. J Immunol Res. 2022 Aug 1;2022:7912484. doi: 10.1155/2022/7912484. eCollection 2022. J Immunol Res. 2022. PMID: 35958877 Free PMC article.
BRD4 PROTAC degrader MZ1 exerts anticancer effects in acute myeloid leukemia by targeting c-Myc and ANP32B genes.
Ma L, Wang J, Zhang Y, Fang F, Ling J, Chu X, Zhang Z, Tao Y, Li X, Tian Y, Li Z, Sang X, Zhang K, Lu L, Wan X, Chen Y, Yu J, Zhuo R, Wu S, Lu J, Pan J, Hu S. Ma L, et al. Among authors: zhang z, zhang k, zhang y. Cancer Biol Ther. 2022 Dec 31;23(1):1-15. doi: 10.1080/15384047.2022.2125748. Cancer Biol Ther. 2022. PMID: 36170346 Free PMC article.
LMO2 promotes the development of AML through interaction with transcription co-regulator LDB1.
Lu L, Wang J, Fang F, Guo A, Jiang S, Tao Y, Zhang Y, Li Y, Zhang K, Zhang Z, Zhuo R, Chu X, Li X, Tian Y, Ma L, Sang X, Chen Y, Yu J, Yang Y, Cao H, Gao J, Lu J, Hu S, Pan J, He H. Lu L, et al. Among authors: zhang z, zhang k, zhang y. Cell Death Dis. 2023 Aug 12;14(8):518. doi: 10.1038/s41419-023-06039-w. Cell Death Dis. 2023. PMID: 37573405 Free PMC article.
The influence of methotrexate-related transporter and metabolizing enzyme gene polymorphisms on peri-engraftment syndrome and graft-versus-host disease after haplo-hematopoietic stem cell transplantation in pediatric patients with malignant hematological diseases.
Ji Q, Zhang Y, Hu Y, Liu L, Cao S, Gao L, Li B, Tian Y, Kong L, Wu S, Ling J, Xiao P, Lu J, Li J, Yao Y, Qin J, Hu S. Ji Q, et al. Among authors: zhang y. Front Immunol. 2023 Sep 5;14:1229266. doi: 10.3389/fimmu.2023.1229266. eCollection 2023. Front Immunol. 2023. PMID: 37731501 Free PMC article.
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