The inositol pyrophosphate 5-InsP7 drives sodium-potassium pump degradation by relieving an autoinhibitory domain of PI3K p85α.
Chin AC, Gao Z, Riley AM, Furkert D, Wittwer C, Dutta A, Rojas T, Semenza ER, Felder RA, Pluznick JL, Jessen HJ, Fiedler D, Potter BVL, Snyder SH, Fu C.
Chin AC, et al. Among authors: riley am.
Sci Adv. 2020 Oct 28;6(44):eabb8542. doi: 10.1126/sciadv.abb8542. Print 2020 Oct.
Sci Adv. 2020.
PMID: 33115740
Free PMC article.