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Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK).
Bressler KR, Ross JA, Ilnytskyy S, Vanden Dungen K, Taylor K, Patel K, Zovoilis A, Kovalchuk I, Thakor N. Bressler KR, et al. Cell Stress Chaperones. 2021 Jan;26(1):253-264. doi: 10.1007/s12192-020-01174-1. Epub 2020 Oct 29. Cell Stress Chaperones. 2021. PMID: 33123915 Free PMC article.
Real-world Clinical Outcomes and Prognostic Factors in Neuroendocrine Prostate Cancer.
Gagnon R, Kish EK, Cook S, Takemura K, Cheng BYC, Bressler K, Heng DYC, Alimohamed N, Ruether D, Lee-Ying RM, Bose P, Kolinsky MP, Vasquez C, Samuel D, Lewis J, Faridi R, Borkar M, Fairey A, Bismar T, Yip S. Gagnon R, et al. Clin Genitourin Cancer. 2024 Nov 23;23(1):102274. doi: 10.1016/j.clgc.2024.102274. Online ahead of print. Clin Genitourin Cancer. 2024. PMID: 39689666 Free article.