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Depletion of eukaryotic initiation factor 5B (eIF5B) reprograms the cellular transcriptome and leads to activation of endoplasmic reticulum (ER) stress and c-Jun N-terminal kinase (JNK).
Bressler KR, Ross JA, Ilnytskyy S, Vanden Dungen K, Taylor K, Patel K, Zovoilis A, Kovalchuk I, Thakor N. Bressler KR, et al. Among authors: vanden dungen k. Cell Stress Chaperones. 2021 Jan;26(1):253-264. doi: 10.1007/s12192-020-01174-1. Epub 2020 Oct 29. Cell Stress Chaperones. 2021. PMID: 33123915 Free PMC article.