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Dynamic stress- and inflammatory-based regulation of psychiatric risk loci in human neurons.
Retallick-Townsley KG, Lee S, Cartwright S, Cohen S, Sen A, Jia M, Young H, Dobbyn L, Deans M, Fernandez-Garcia M, Huckins LM, Brennand KJ. Retallick-Townsley KG, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2024 Jul 9:2024.07.09.602755. doi: 10.1101/2024.07.09.602755. bioRxiv. 2024. PMID: 39026810 Free PMC article. Preprint.
Common genetic variation impacts stress response in the brain.
Seah C, Signer R, Deans M, Bader H, Rusielewicz T, Hicks EM, Young H, Cote A, Townsley K, Xu C, Hunter CJ, McCarthy B, Goldberg J, Dobariya S, Holtzherimer PE, Young KA; NYSCF Global Stem Cell Array® Team; Traumatic Stress Brain Research Group; Noggle SA, Krystal JH, Paull D, Girgenti MJ, Yehuda R, Brennand KJ, Huckins LM. Seah C, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2023 Dec 28:2023.12.27.573459. doi: 10.1101/2023.12.27.573459. bioRxiv. 2023. PMID: 38234801 Free PMC article. Preprint.
Decoding the transcriptomic signatures of psychological trauma in human cortex and amygdala.
Hicks EM, Seah C, Deans M, Lee S, Johnston KJA, Cote A, Ciarcia J, Chakka A, Collier L, Holtzheimer PE, Young KA; Traumatic Stress Brain Research Group; Krystal JH, Brennand KJ, Nestler EJ, Girgenti MJ, Huckins LM. Hicks EM, et al. Among authors: brennand kj. bioRxiv [Preprint]. 2024 Oct 23:2024.10.23.619681. doi: 10.1101/2024.10.23.619681. bioRxiv. 2024. PMID: 39484441 Free PMC article. Preprint.
A role for noncoding variation in schizophrenia.
Roussos P, Mitchell AC, Voloudakis G, Fullard JF, Pothula VM, Tsang J, Stahl EA, Georgakopoulos A, Ruderfer DM, Charney A, Okada Y, Siminovitch KA, Worthington J, Padyukov L, Klareskog L, Gregersen PK, Plenge RM, Raychaudhuri S, Fromer M, Purcell SM, Brennand KJ, Robakis NK, Schadt EE, Akbarian S, Sklar P. Roussos P, et al. Among authors: brennand kj. Cell Rep. 2014 Nov 20;9(4):1417-29. doi: 10.1016/j.celrep.2014.10.015. Epub 2014 Nov 6. Cell Rep. 2014. PMID: 25453756 Free PMC article.
Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Fromer M, Roussos P, Sieberts SK, Johnson JS, Kavanagh DH, Perumal TM, Ruderfer DM, Oh EC, Topol A, Shah HR, Klei LL, Kramer R, Pinto D, Gümüş ZH, Cicek AE, Dang KK, Browne A, Lu C, Xie L, Readhead B, Stahl EA, Xiao J, Parvizi M, Hamamsy T, Fullard JF, Wang YC, Mahajan MC, Derry JM, Dudley JT, Hemby SE, Logsdon BA, Talbot K, Raj T, Bennett DA, De Jager PL, Zhu J, Zhang B, Sullivan PF, Chess A, Purcell SM, Shinobu LA, Mangravite LM, Toyoshiba H, Gur RE, Hahn CG, Lewis DA, Haroutunian V, Peters MA, Lipska BK, Buxbaum JD, Schadt EE, Hirai K, Roeder K, Brennand KJ, Katsanis N, Domenici E, Devlin B, Sklar P. Fromer M, et al. Among authors: brennand kj. Nat Neurosci. 2016 Nov;19(11):1442-1453. doi: 10.1038/nn.4399. Epub 2016 Sep 26. Nat Neurosci. 2016. PMID: 27668389 Free PMC article.
Spatial genome organization and cognition.
Rajarajan P, Gil SE, Brennand KJ, Akbarian S. Rajarajan P, et al. Among authors: brennand kj. Nat Rev Neurosci. 2016 Nov;17(11):681-691. doi: 10.1038/nrn.2016.124. Epub 2016 Oct 6. Nat Rev Neurosci. 2016. PMID: 27708356 Free PMC article. Review.
MEF2C transcription factor is associated with the genetic and epigenetic risk architecture of schizophrenia and improves cognition in mice.
Mitchell AC, Javidfar B, Pothula V, Ibi D, Shen EY, Peter CJ, Bicks LK, Fehr T, Jiang Y, Brennand KJ, Neve RL, Gonzalez-Maeso J, Akbarian S. Mitchell AC, et al. Among authors: brennand kj. Mol Psychiatry. 2018 Jan;23(1):123-132. doi: 10.1038/mp.2016.254. Epub 2017 Jan 24. Mol Psychiatry. 2018. PMID: 28115742 Free PMC article.
157 results