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Panels of chemically-modified heparin polysaccharides and natural heparan sulfate saccharides both exhibit differences in binding to Slit and Robo, as well as variation between protein binding and cellular activity.
Ahmed YA, Yates EA, Moss DJ, Loeven MA, Hussain SA, Hohenester E, Turnbull JE, Powell AK. Ahmed YA, et al. Among authors: yates ea. Mol Biosyst. 2016 Oct 20;12(10):3166-75. doi: 10.1039/c6mb00432f. Epub 2016 Aug 9. Mol Biosyst. 2016. PMID: 27502551 Free PMC article.
164 results