Zheng X - Search Results

1

Design, synthesis and antitumor evaluation of novel 5-methylpyrazolo[1,5-a]pyrimidine derivatives as potential c-Met inhibitors.

Luo G, Ma Y, Liang X, Xie G, Luo Y, Zha D, Wang S, Yu L, Zheng X, Wu W, Zhang C. Luo G, et al. Among authors: zheng x. Bioorg Chem. 2020 Nov;104:104356. doi: 10.1016/j.bioorg.2020.104356. Epub 2020 Oct 8. Bioorg Chem. 2020. PMID: 33142417

2

3D-QSAR studies of 3-(3,4-dihydroisoquinolin-2(1H)-ylsulfonyl)benzoic acids as AKR1C3 inhibitors: Highlight the importance of molecular docking in conformation generation.

Zheng X, Wu Y, Wu D, Wang X, Zhang C, Guo X, Luo HB. Zheng X, et al. Bioorg Med Chem Lett. 2016 Dec 1;26(23):5631-5638. doi: 10.1016/j.bmcl.2016.10.073. Epub 2016 Nov 1. Bioorg Med Chem Lett. 2016. PMID: 27847272

3

Synthesis and Evaluation of Novel Ligustrazine Derivatives as Multi-Targeted Inhibitors for the Treatment of Alzheimer's Disease.

Wu W, Liang X, Xie G, Chen L, Liu W, Luo G, Zhang P, Yu L, Zheng X, Ji H, Zhang C, Yi W. Wu W, et al. Among authors: zheng x. Molecules. 2018 Oct 5;23(10):2540. doi: 10.3390/molecules23102540. Molecules. 2018. PMID: 30301153 Free PMC article.

4

Screening, synthesis, crystal structure, and molecular basis of 6-amino-4-phenyl-1,4-dihydropyrano[2,3-c]pyrazole-5-carbonitriles as novel AKR1C3 inhibitors.

Zheng X, Jiang Z, Li X, Zhang C, Li Z, Wu Y, Wang X, Zhang C, Luo HB, Xu J, Wu D. Zheng X, et al. Bioorg Med Chem. 2018 Dec 1;26(22):5934-5943. doi: 10.1016/j.bmc.2018.10.044. Epub 2018 Nov 3. Bioorg Med Chem. 2018. PMID: 30429100

5

Design, Synthesis and Cytotoxicity Evaluation of Novel Indole Derivatives Containing Benzoic Acid Group as Potential AKR1C3 Inhibitors.

Sun M, Zhou Y, Zhuo X, Wang S, Jiang S, Peng Z, Kang K, Zheng X, Sun M. Sun M, et al. Among authors: zheng x. Chem Biodivers. 2020 Dec;17(12):e2000519. doi: 10.1002/cbdv.202000519. Epub 2020 Nov 24. Chem Biodivers. 2020. PMID: 33111427

6

The novel indomethacin derivative CZ-212-3 exerts antitumor effects on castration-resistant prostate cancer by degrading androgen receptor and its variants.

Wang H, Chang Z, Cai GD, Yang P, Chen JH, Yang SS, Guo YF, Wang MY, Zheng XH, Lei JP, Liu PQ, Zhao DP, Wang JJ. Wang H, et al. Acta Pharmacol Sin. 2022 Apr;43(4):1024-1032. doi: 10.1038/s41401-021-00738-w. Epub 2021 Jul 28. Acta Pharmacol Sin. 2022. PMID: 34321613 Free PMC article.

7

Inhibition of AKR1Cs by liquiritigenin and the structural basis.

Liu H, Yao Z, Sun M, Zhang C, Huang YY, Luo HB, Wu D, Zheng X. Liu H, et al. Among authors: zheng x. Chem Biol Interact. 2023 Nov 1;385:110654. doi: 10.1016/j.cbi.2023.110654. Epub 2023 Sep 2. Chem Biol Interact. 2023. PMID: 37666442

8

Discovery of new selective human aldose reductase inhibitors through virtual screening multiple binding pocket conformations.

Wang L, Gu Q, Zheng X, Ye J, Liu Z, Li J, Hu X, Hagler A, Xu J. Wang L, et al. Among authors: zheng x. J Chem Inf Model. 2013 Sep 23;53(9):2409-22. doi: 10.1021/ci400322j. Epub 2013 Aug 26. J Chem Inf Model. 2013. PMID: 23901876

9

The discovery, complex crystal structure, and recognition mechanism of a novel natural PDE4 inhibitor from Selaginella pulvinata.

Huang Y, Liu X, Wu D, Tang G, Lai Z, Zheng X, Yin S, Luo HB. Huang Y, et al. Among authors: zheng x. Biochem Pharmacol. 2017 Apr 15;130:51-59. doi: 10.1016/j.bcp.2017.01.016. Epub 2017 Jan 31. Biochem Pharmacol. 2017. PMID: 28159622

10

Quantitative structure-retention relationship of curcumin and its analogues.

Zheng XH, Shao YX, Li Z, Liu M, Bu X, Luo HB, Hu X. Zheng XH, et al. J Sep Sci. 2012 Feb;35(4):505-12. doi: 10.1002/jssc.201100903. J Sep Sci. 2012. PMID: 22282411

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