Wikoff D - Search Results

1

Application of the DILIsym® Quantitative Systems Toxicology drug-induced liver injury model to evaluate the carcinogenic hazard potential of acetaminophen.

Eichenbaum G, Yang K, Gebremichael Y, Howell BA, Murray FJ, Jacobson-Kram D, Jaeschke H, Kuffner E, Gelotte CK, Lai JCK, Wikoff D, Atillasoy E. Eichenbaum G, et al. Among authors: wikoff d. Regul Toxicol Pharmacol. 2020 Dec;118:104788. doi: 10.1016/j.yrtph.2020.104788. Epub 2020 Oct 22. Regul Toxicol Pharmacol. 2020. PMID: 33153971 Free article.

2

A high dose mode of action for tetrabromobisphenol A-induced uterine adenocarcinomas in Wistar Han rats: A critical evaluation of key events in an adverse outcome pathway framework.

Wikoff DS, Rager JE, Haws LC, Borghoff SJ. Wikoff DS, et al. Regul Toxicol Pharmacol. 2016 Jun;77:143-59. doi: 10.1016/j.yrtph.2016.01.018. Epub 2016 Jan 28. Regul Toxicol Pharmacol. 2016. PMID: 26828025 Free article. Review.

3

Development of linear and threshold no significant risk levels for inhalation exposure to titanium dioxide using systematic review and mode of action considerations.

Thompson CM, Suh M, Mittal L, Wikoff DS, Welsh B, Proctor DM. Thompson CM, et al. Regul Toxicol Pharmacol. 2016 Oct;80:60-70. doi: 10.1016/j.yrtph.2016.05.031. Epub 2016 May 24. Regul Toxicol Pharmacol. 2016. PMID: 27233922 Review.

4

Systematic evaluation of mechanistic data in assessing in utero exposures to trichloroethylene and development of congenital heart defects.

Urban JD, Wikoff DS, Chappell GA, Harris C, Haws LC. Urban JD, et al. Among authors: wikoff ds. Toxicology. 2020 Apr 30;436:152427. doi: 10.1016/j.tox.2020.152427. Epub 2020 Mar 4. Toxicology. 2020. PMID: 32145346 Free article.

5

Facilitation of risk assessment with evidence-based methods - A framework for use of systematic mapping and systematic reviews in determining hazard, developing toxicity values, and characterizing uncertainty.

Wikoff D, Lewis RJ, Erraguntla N, Franzen A, Foreman J. Wikoff D, et al. Regul Toxicol Pharmacol. 2020 Dec;118:104790. doi: 10.1016/j.yrtph.2020.104790. Epub 2020 Oct 7. Regul Toxicol Pharmacol. 2020. PMID: 33038430 Free article.

6

Assessment of the biochemical pathways for acetaminophen toxicity: Implications for its carcinogenic hazard potential.

Jaeschke H, Murray FJ, Monnot AD, Jacobson-Kram D, Cohen SM, Hardisty JF, Atillasoy E, Hermanowski-Vosatka A, Kuffner E, Wikoff D, Chappell GA, Bandara SB, Deore M, Pitchaiyan SK, Eichenbaum G. Jaeschke H, et al. Among authors: wikoff d. Regul Toxicol Pharmacol. 2021 Mar;120:104859. doi: 10.1016/j.yrtph.2020.104859. Epub 2021 Jan 1. Regul Toxicol Pharmacol. 2021. PMID: 33388367 Free article. Review.

7

Development and application of a systematic and quantitative weighting framework to evaluate the quality and relevance of relative potency estimates for dioxin-like compounds (DLCs) for human health risk assessment.

Wikoff D, Ring C, DeVito M, Walker N, Birnbaum L, Haws L. Wikoff D, et al. Regul Toxicol Pharmacol. 2023 Dec;145:105500. doi: 10.1016/j.yrtph.2023.105500. Epub 2023 Oct 21. Regul Toxicol Pharmacol. 2023. PMID: 37866700 Free PMC article.

8

Development of toxicity values and exposure estimates for tetrabromobisphenol A: application in a margin of exposure assessment.

Wikoff D, Thompson C, Perry C, White M, Borghoff S, Fitzgerald L, Haws LC. Wikoff D, et al. J Appl Toxicol. 2015 Nov;35(11):1292-308. doi: 10.1002/jat.3132. Epub 2015 Mar 30. J Appl Toxicol. 2015. PMID: 25825072 Free PMC article.

9

Role of Risk of Bias in Systematic Review for Chemical Risk Assessment: A Case Study in Understanding the Relationship Between Congenital Heart Defects and Exposures to Trichloroethylene.

Wikoff D, Urban JD, Harvey S, Haws LC. Wikoff D, et al. Int J Toxicol. 2018 Mar/Apr;37(2):125-143. doi: 10.1177/1091581818754330. Epub 2018 Jan 22. Int J Toxicol. 2018. PMID: 29357719 Free PMC article.

10

Application of qualitative and quantitative uncertainty assessment tools in developing ranges of plausible toxicity values for 2,3,7,8-tetrachlorodibenzo-p-dioxin.

Wikoff D, Haws L, Ring C, Budinsky R. Wikoff D, et al. J Appl Toxicol. 2019 Sep;39(9):1293-1310. doi: 10.1002/jat.3814. Epub 2019 Jun 30. J Appl Toxicol. 2019. PMID: 31257608 Free PMC article.

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