Najafov A - Search Results

1

Pharmacological targeting of MCL-1 promotes mitophagy and improves disease pathologies in an Alzheimer's disease mouse model.

Cen X, Chen Y, Xu X, Wu R, He F, Zhao Q, Sun Q, Yi C, Wu J, Najafov A, Xia H. Cen X, et al. Among authors: najafov a. Nat Commun. 2020 Nov 12;11(1):5731. doi: 10.1038/s41467-020-19547-6. Nat Commun. 2020. PMID: 33184293 Free PMC article.

2

ARIH1 signaling promotes anti-tumor immunity by targeting PD-L1 for proteasomal degradation.

Wu Y, Zhang C, Liu X, He Z, Shan B, Zeng Q, Zhao Q, Zhu H, Liao H, Cen X, Xu X, Zhang M, Hou T, Wang Z, Yan H, Yang S, Sun Y, Chen Y, Wu R, Xie T, Chen W, Najafov A, Ying S, Xia H. Wu Y, et al. Among authors: najafov a. Nat Commun. 2021 Apr 20;12(1):2346. doi: 10.1038/s41467-021-22467-8. Nat Commun. 2021. PMID: 33879767 Free PMC article.

3

Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.

Xu X, Sun Y, Cen X, Shan B, Zhao Q, Xie T, Wang Z, Hou T, Xue Y, Zhang M, Peng D, Sun Q, Yi C, Najafov A, Xia H. Xu X, et al. Among authors: najafov a. Protein Cell. 2021 Oct;12(10):769-787. doi: 10.1007/s13238-021-00858-3. Epub 2021 Jul 21. Protein Cell. 2021. PMID: 34291435 Free PMC article.

4

Correction to: Metformin activates chaperone-mediated autophagy and improves disease pathologies in an Alzheimer disease mouse model.

Xu X, Sun Y, Cen X, Shan B, Zhao Q, Xie T, Wang Z, Hou T, Xue Y, Zhang M, Peng D, Sun Q, Yi C, Najafov A, Xia H. Xu X, et al. Among authors: najafov a. Protein Cell. 2022 Mar;13(3):227-229. doi: 10.1007/s13238-021-00873-4. Protein Cell. 2022. PMID: 34725788 Free PMC article. No abstract available.

5

RIPK1 Promotes Energy Sensing by the mTORC1 Pathway.

Najafov A, Luu HS, Mookhtiar AK, Mifflin L, Xia HG, Amin PP, Ordureau A, Wang H, Yuan J. Najafov A, et al. Mol Cell. 2021 Jan 21;81(2):370-385.e7. doi: 10.1016/j.molcel.2020.11.008. Epub 2020 Dec 2. Mol Cell. 2021. PMID: 33271062 Free article.

6

Degradation of HK2 by chaperone-mediated autophagy promotes metabolic catastrophe and cell death.

Xia HG, Najafov A, Geng J, Galan-Acosta L, Han X, Guo Y, Shan B, Zhang Y, Norberg E, Zhang T, Pan L, Liu J, Coloff JL, Ofengeim D, Zhu H, Wu K, Cai Y, Yates JR, Zhu Z, Yuan J, Vakifahmetoglu-Norberg H. Xia HG, et al. Among authors: najafov a. J Cell Biol. 2015 Aug 31;210(5):705-16. doi: 10.1083/jcb.201503044. J Cell Biol. 2015. PMID: 26323688 Free PMC article.

7

G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L.

Zhang T, Dong K, Liang W, Xu D, Xia H, Geng J, Najafov A, Liu M, Li Y, Han X, Xiao J, Jin Z, Peng T, Gao Y, Cai Y, Qi C, Zhang Q, Sun A, Lipinski M, Zhu H, Xiong Y, Pandolfi PP, Li H, Yu Q, Yuan J. Zhang T, et al. Among authors: najafov a. Elife. 2015 Mar 30;4:e06734. doi: 10.7554/eLife.06734. Elife. 2015. PMID: 25821988 Free PMC article.

8

NEK1-mediated retromer trafficking promotes blood-brain barrier integrity by regulating glucose metabolism and RIPK1 activation.

Wang H, Qi W, Zou C, Xie Z, Zhang M, Naito MG, Mifflin L, Liu Z, Najafov A, Pan H, Shan B, Li Y, Zhu ZJ, Yuan J. Wang H, et al. Among authors: najafov a. Nat Commun. 2021 Aug 10;12(1):4826. doi: 10.1038/s41467-021-25157-7. Nat Commun. 2021. PMID: 34376696 Free PMC article.

9

Modulating TRADD to restore cellular homeostasis and inhibit apoptosis.

Xu D, Zhao H, Jin M, Zhu H, Shan B, Geng J, Dziedzic SA, Amin P, Mifflin L, Naito MG, Najafov A, Xing J, Yan L, Liu J, Qin Y, Hu X, Wang H, Zhang M, Manuel VJ, Tan L, He Z, Sun ZJ, Lee VMY, Wagner G, Yuan J. Xu D, et al. Among authors: najafov a. Nature. 2020 Nov;587(7832):133-138. doi: 10.1038/s41586-020-2757-z. Epub 2020 Sep 23. Nature. 2020. PMID: 32968279

10

Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis.

Geng J, Ito Y, Shi L, Amin P, Chu J, Ouchida AT, Mookhtiar AK, Zhao H, Xu D, Shan B, Najafov A, Gao G, Akira S, Yuan J. Geng J, et al. Among authors: najafov a. Nat Commun. 2017 Aug 25;8(1):359. doi: 10.1038/s41467-017-00406-w. Nat Commun. 2017. PMID: 28842570 Free PMC article.

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